HealingWell
Search Close Search
☰

Lactoferrin shows promise for COVID treatment

Support Forums
>
Lyme Disease
✚ New Topic ✚ Reply
❬ ❬ Previous Thread |Next Thread ❭ ❭
Posted 10/28/2020 8:45 PM (GMT 0)
Liposomal Lactoferrin as Potential Preventative and Cure for COVID-19:
https://www.fulltxt.org/article/1060

A prospective observational study was performed in 75 patients with typical symptoms of COVID-19 who tested positive to IgM/IgG rapid test. Patients were isolated and treated at home using remote systems, reviewed twice a day for 10 days, and followed up to 1 month. A liposomal bovine lactoferrin (LLF) nutritional syrup food supplement (32 mg of LF/10 ml plus 12 mg of vitamin C) was administered orally in 4 to 6 doses per day for 10 days. In addition, a zinc solution was administered at the dose of 10 mg/10 ml twice or three times a day. A control group of 12 patients who took only LLF was included. All family members in contact with patients (256 persons) were also treated with half of this dose. The treatment allowed a complete and fast recovery in all patients (100%) within the first 4-5 days. Same treatment at lower dose prevented the disease in healthy persons directly related with the affected patients. Weakness (95%) followed by a dysfunction in the perception of smelling and tasting (88%), cough (83%), muscular pain (67%) were the most frequent complains. LF possess antiviral, immunomodulatory and anti-inflammatory effects which might be important for the treatment of COVID-19 infection. We conclude that LLF potentially prevent and cure COVID 19 infection.
Posted 10/28/2020 8:47 PM (GMT 0)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271924/
In COVID-19 infection, Lactoferrin may have a role to play in not only sequestering iron and inflammatory molecules that are severely increased during the cytokine burst, but also possibly in assisting in occupying receptors and HSPGs to prevent virus binding. Receptor occupancy is an important characteristic of Lactoferrin, when taken as supplement. Furthermore, it may assist in preventing thrombocytopenia, and hypercoagulation, both prominent features of COVID-19 infection.

--> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271924/bin/fimmu-11-01221-g0006.jpg

Possible action of (1) lactoferrin by occupying binding sites of (2) SARS-CoV-2 that causes COVID-19. (3) Entry into host cells occur when SARS-CoV-2 first attaches to Heparan sulfate proteoglycans (HSPGs). This attachment initiates the first contact between the cell and the virus, concentrating the virus on the cell surface, (4) followed attaching of the virus to the host receptor (ACE2) and association and entering are then facilitated via clathrin-coated pits (5) Virus replication can then happen inside the cell. (6) One of the characteristics of Lactoferrin, is that it attaches to HSPGs. (7) Currently we do not know if ACE2 is also a receptor for lactoferrin. (8) Lactoferrin may block the entry of SARS-CoV-2 into the host cell, by occupying HPSGs, thereby preventing SARS-CoV-2 initial attachment and accumulation on the host cell membrane.
Posted 10/28/2020 9:29 PM (GMT 0)
Interesting - I take lactoferrin - Dr J has all patients on it.

Maybe that’s why I didn’t get covid when my husband did
Posted 10/28/2020 9:54 PM (GMT 0)
This is very interesting. I'm curious why a dermatology lab in Spain did this study, but hey, we'll take what we can get.
Posted 10/28/2020 11:09 PM (GMT 0)
Pleiotropic effect of Lactoferrin in the prevention and treatment of COVID-19 infection: in vivo, in silico and in vitro preliminary evidences
https://www.biorxiv.org/content/10.1101/2020.08.11.244996v1.full
Posted 10/29/2020 1:44 AM (GMT 0)
Girlie,

What brand of lactoferrin do you use and at what dosage?
Posted 10/29/2020 7:20 AM (GMT 0)

WalkingbyFaith said...
Girlie,

What brand of lactoferrin do you use and at what dosage?

It might be Jarrow.. but I’m laying in bed right now - too lazy to go check.
I’ll hopefully remember in the morning and will post with dosage.
Posted 10/29/2020 5:22 PM (GMT 0)
The brand is AOR

250 mg per capsule

I take two caps once daily - only 3 days per month (this is for my lyme maintenance protocol not covid)

(Edited : I had previously wrote twice daily - but it's just in the morning)

I did take the lactoferrin Monday to Friday on Week 1 of my persister's protocols. That was for approximately 6 months - prior to my maintenance protocol.
✚ New Topic ✚ Reply