I actually think its a form of neuroinflammation. The glial cells get activated which causes them to keep emitting cytokines, which upregulates gluamate and ion channels and you have neurodegeneration.
I think CRPS is a different form of the same problem. So is what I have. So is CFS. Seizures. Buzzing sensations. PANS, all of these non-specific neuro diseases are different flavors of this.
I went to a PhD researcher in neuropsyche and he had this cool tool where he basically puts one of those seizure nets on your head. It looks at 32 different points in the head and measures them, to see which are in sync and talking to each other. This creates something lke 10,000 variables, which he regresses against a database of people with TBI. Told me >95% probability I had a TBI. It showed up on my PET MRI too in the hippocampus. I've never had a physical trauma though though, knock on wood. I was diagnosed with glutamate induced vestibular migraines though. I also have neuroinflammation of the spine (which is causing this buzzing sesnation) and peripheral nerves (hence the neuropathy). Point being, I've got a simlar mishmash and its inflammatory and you see it across a whole bunch of diseases. Prob result of an infection or toxin, the nerves are fine and calm until they get exposed to too many neurotoxins, and freak out permanently. Very hard to calm them down. This is why i was doing ketamine. Might try minocycline too, supposed to be great for calming glial cells. LDN helpful. Exosomes could potentially be too. Also looking into the COIMBRA protocol. Vit D lowers PTH which reduces calcium levels and calms these ion channels down. It's not a coincidence that ion-channel antagonists like mexilitine and ketamine reduce pain and induce neuro-plasticity, calms that exciatory inflammation.
He's saying it's basically a chronic on-going TBI, and he's right. But not because "our connective tissue cant support our body", but because of this inflammatory reponse. He mentions EDS which is a disease of the connective tissues, but people w/ EDS often have neurodegeneration and tend to develop CRPS, telling you its an ion-channel/excitatory/inflammatory response, probably genetic in that case.
Post Edited (dcd2103) : 2/19/2021 11:57:46 AM (GMT-7)