Has anyone tried Topiramate for migrane prevention?

I did try topiramate or Topamax its called also. I was on it about 2 months. It may have taken a few migraines but it also made me lose my memory, made me very shaky and lethargic. I stopped taking it and finally went to a neurologist. After some coaxing to find a different drug he prescribed an antihistamine!!! Twice a day. I was having at least 3 migraines a week and some lasted 3,4, and 5 days. After being on this drud only a few days they were gone!! It has been 2 years and I have had 3 migraines!!!!!! It is wonderful to not have them anymore. It wasn't just migraines. If I didn't have a migraine I had some kind of headache everyday. My head was never Clear. Now it is. I would suggest asking to try a antihistamine. You have nothing to lose but the migraines!

My GP put me on Topamax when my migraines started to increase in frequency and intensity.  This was about 3 years ago and I as on it for 4 months.  While I did see a drop in migraines the side effects were so bad I felt worse than before.  Many chat rooms kept saying you just needed to stick with it and the side effects would go away.  I couldn't wait.  I went to a neurologist who unfortunately put me on a generic form (Zogran ?) along with Cymbalta and Zomig.  Little did I know at the time, but Cymbalta (or any SSRI) and Zomig (or any triptan) are contraindicated and it sent me into the hospital with serotonin syndrome.  I now can never take another serotonergic drug.  The moral of the story is to do your homework.  My husband, not my wonderful neurologist diagnosed my problem.  You must be your own advocate no matter what course you deside to try!

Had terrible side effects from Topomax. stomach ache, nausea, stomach cramps, weight loss, tingling feeling in hands and toes, slight depression, change in taste... and the migrains didn't go away.

I did start with a low dose and slowly increased, so that wasn't the answer.

I tried beta blockers and it didn't help (I have slightly high BP anyway), then my Gastroenterologist switched me from beta blocker to calcium channel blockers for my esophageal spasms, and I haven't had a migraine in about 3 months!

I still get ocassional headaches, but they're not migraines, and tylenol usually takes care of them.

My Dr never suggested antihistamines, worth a try!

Best of luck!

I tried Topomax for a period of about three months. I started at 25 and worked all the way up to 200mg daily. I suffer from migraines and tension headaches. Unfortunately I suffered horrible tingling sensations from my elbows down and from my knees down. It was so bad that I lost dexterity in my hands. My friend was on it previously and had similar problems but said that the tingling went away after a few days. I waited the entire three months and the tingling never went away- it just got worse with increasing doses. I also began having eye muscle twitching and facial tingliness at the highest dose. I ultimately stopped the drug because of this, but it did help a little with my headache incidence. My friend was one of the unlucky ones that got kidney stones from Topomax, which she was on for more than a year and a half. She actually experienced weight loss with this drug, but I did not. My neurologist said later that it is the people that have the tingling sensations that seem to have the most benefit from the drug. Good luck if you try it!