Younger men = more aggressive PC?

Last year maybe..this year the opinion is different!!

Truth is probably more likely that younger men will no doubt spread if left untreated for long. Also, younger men aren't tested early enough to catch earlier stage cancers still. The most Agressive types may have a genetic link.

I've often wondered if our younger men presenting with cancers are part of the chemical / hormone (especially hormones) additive generation. The 30-40 somethings would be in that first generation of heavily produced preservative, chemical and horomone enhanced products.

swim

JerseyG, If that was the case then why do I have aggressive PCa at the age of 67? I agree that gennes has something to do with that. My father had PC and my brother also did although he died of a heart attack and not PCa.

Thnking again about what I want to post it seems a very unlikely explanation, but one urologist I saw told me that PCa in younger guys is often aggressive because a less aggressive cancer would have been "dealt with" by the body. It made sense to me at the time, but now it sounds strange. I never heard of the body blocking out a weak cancer. In any case, mine started off with low PSAs and a mid-range Gleason, but the pathology said it had reached to less than 1mm from the capsule by the time it was removed, so I eternally grateful that it was found when it was.

I've also heard that for cancer in general, cancer in younger people tends to be more aggressive.

Tony, This is very interesting data that you bring up... Breast cancer among younger women is often thought to be more agressive than the cancer after menopause. My mother died of breast cancer at 50..... Pete, my husband, who is a scientist, believes that his cancer, found earlier than his father's. (who died at 95) of something else, may have something to do with Vitamin D3.... The main thinking in this family is: No one as yet, knows why, how, or what started the cancer.....AND we are hoping for genetic science to bring more light to this cancer, and how to treat it at each stage. African American men in the northern climates often have higher incidences of cancer maybe because of Vitamin D ....The skin does not assimilate Vit D....The farther north ..the more incidence of prostate AND breast cancer....Vitamin D is a hormone....not just a vitamin, and the 400 units that the government regulated was because of rickets in children in much earlier years....I dont say this is the reason for prostate or breast cancer, I am just suggesting that it should be looked at as a possible contributor.....By the way, we are taking over 2000 units a day......Diane

I don't think that there is any hard evidence to support that younger men get more aggressive cancer. Aggressive cancer is about 20-30% of all PC and 70% -80% cure rates and the 30% reoccurrance rates are in this range. I don't think think is a difference in either cure rates or reoccurrance rates between younger or older men.
The data Tony posted is in this range, but from the data it seems that in the above 80 group the cancer has gotten more aggressive most likely because it has been around a lot longer, 20-30 years.
JT

Squirm,

No symptoms, during my annual physical the doc felt "something" while performing DRE. That led to a biopsy. Biopsy was positive in 3 of 12 cores.  Gleason 6.