My urologist gave me 30cc of trimix in his office as a test a month ago, and it worked pretty well but I had pretty bad aching. He said the aching would get better over time, and asked me to come back once he had mixed up a batch for me to take home. This is a real advantage for me, because he mixes it up at the military clinic where I go. I returned a couple of weeks ago and he gave me the 30cc again, and this time it didn't ache as much, but I didn't think it was strong enough for penetration. He said to increase the dose to 35 then to 40 and if that didn't work to go back to see him.
I tried it at home a week ago, at 30 cc, and it was about the same as at the doctors office, good response but not enough for penetration. The erection lasted about 1 1/2 hours, which the doctor said was the right duration.
Yesterday I increased the dose to 35cc and it did the trick, strong enough for penetration. It lasted almost two hours, and it didn't ache as much as the first time but it was still pretty tender. When I put on my pants, just the pressure of the clothing made it ache, so I wore pretty lose clothes until it went down.
The feeling was good, although to be honest it didn't feel quite the same as a natural erection. The main difference, I think, is the ache that I feel when there is any pressure on. I hope that decreases over time. Doc wants me to try it a couple of times a week and go back to see him in two months.
All in all my wife and I are very grateful for the trimix, it gives us renewed hope for the ED after surgery. This is the last problem we have, since the PSA is still 0 and I remain continent.