DW,
I have used Trimix for over a year now, I am 19 months post op. I started with .20 and worked my way up the progression ladder until I reached .50; this seemed to be the “sweet spot” for me. However, as time progressed I found that I needed less and less to achieve the desired results. I am now using .15 to .20 with very good results. If you’re not having trouble with .40 it’s likely that you will not have issues with increasing to .50. Of course, I’m not a doctor; I can only share my experiences with this. Another thing that will get better with time is your technique, and your ability to inject yourself. There was a learning curve for me and it probably took me longer than most people to learn the technique that worked best for me. Trimix has been a real blessing to me. It has boosted my confidence level and helped me deal with one of the many side effects of this disease.
Lynn