Here's an abstract that shows comparisons in biopsies using color doppler vs. standard targeted biopsies. Simply states 2.6 times more likely to find PCa using CDU and/or patient could be subjected to lesser numbers of actual biopsies using such technology. The master is Dr. Fred Lee whom has the most experience with this over a few decades now and he has some kind of enhancement added (I heard through the grapevine). Dr. Lee discovered his own PCa upon using this machine like 32 yrs. ago now. His protege here in Michigan years ago was Dr. Duke Bahn whom moved out to California.
Friend of mine went in for CDU not long ago now, and Dr. Lee saw some areas (red showing up- for possible more blood flow activity) and so did biopsies on Rick K. accordingly and even though suspecious areas could have been cancerous, in Rick's unique case nothing was found on his biopsies, although he was detected back in 1995-6 era and decided upon ADT3 drug therapy per Dr. Liebowitz concept as his primary treatment. He has been rebiopsied 3 times over the years since 1995-6 and so far nothing is found, not claiming cured or such but his results are very noteworthy. (he has psa of 11.0 and 2 positive biopsies back then (2+3)=5 so on todays revision scale would be Gleason 6's).
http://prostate.tju.edu/papers/targeted-biop-jurol.pdf