Here's my comments, based on my own non-scientific observations and experiences.
First, I wouldn't do it myself. I had the GL 15 months ago and I found that all of the adverse effects affected me at about
10x the advertised amount.
Second, everyone is different, but I personally have found cipro to be the very best antibiotic, provided I observe the correct way to use it. I have had 14 days x 1000mg/ day several times in the last two years, once I had 28 days x 1000mg / day and have never had a problem. It really works for me to cure UTI's. It can cause some vivid dreams and can also cause a bit of insomnia, making it a bit harder to get to sleep, but otherwise it has worked really well for me so far. Another antibiotic in the same family, Levaquin, didn't work for me at all and gave me really weird dreams and drenching night sweats that saturated my clothes, pillow and sheets in a few hours. One thing I have found out about
cipro is you shouldn't take any form of caffeine while taking it, because cipro prevents caffeine from leaving the body. So I will have one small cup of coffee on the first day and don't have another until I stop the cipro. You also have to space your dairy (eg yogurt to replace stomach flora) so it doesn't react to the cipro. If I am taking one cipro every 12 hours, I have my yogurt exactly at the six hour mark. I have also been taking one 500mg cipro once a week after self cathing, and haven't had any uti's in months, or any noticeable side effects.
Third, with my GL I had "conscious sedation" IV Propofol (my wife said, ooh, you got Michael Jackson juice) and it was excellent. It's like turning a light switch on and off. Out in seconds, and awake in seconds when it stops. No grogginess or after effects at all. Really excellent.
Fourth, I'd opt for Vicodin (tylenol with codeine) for pain. I popped one after waking in really bad pain from the GL and it quieted everything down in less than 10 minutes, and lasts for about
6 hours. Once again, everyone is different, but I find codeine really kills the pain for me.
Fifth, I don't think bleeding is a big issue. I bled like a slaughtered pig for about
9 weeks, every time I urinated the bowl looked like burgundy wine. But other than the aesthetics, it really had no effect.
Finally, I personally have no luck with the advertised results. All the adjectives used to describe the possible side effects of this procedure probably apply to the GL and any other prostate or bladder surgery. And some people reported having a GL, going out to dinner and drinks afterwards, and playing 18 holes of golf the next day. My experience was more like falling off the roof of my house and recuperating slowly and painfully for more than two months. They also say here that re-operation might be necessary in 2-1/2 years with this procedure. To me that means it might be necessary in 6 months if you are not so lucky.
DE-Marshall said...
Hi Guys,
I did some more research on the PAE program. I talked to the folks in Minnesota who are engaged in trails of the procedure. There seems to be much more risks than with the Gat-Goren method. In american they tend to over medicate so I don't know why this procedure is more risky that GG. The Hugh red flag is Cipro. This class of antibiotics was for emergency use only. It can cause permanent brain damage and effect your entire nervous system. I would never take this drug. NEVER. so that said, there are other substitutes one can use. Here is the patient information.
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Preparing for the embolization procedure:
1. Stop all prostate medication 1 week before the procedure.
2. Start an acid suppressing drug (omeprazole 20 mg once daily) and an anti-inflammatory agent (Ibuprofen 800 mg twice daily) for 2 days before the procedure and continue to take them for 7 days after the procedure. These are available as over-the-counter (non-prescription) medications.
3. Take an antibiotic called Cipro 750 mg twice a day for 10 days (start two days prior to the procedure). You will need a prescription from a physician for this. ( you must be joking!)
4. Do not eat anything after midnight prior to the procedure.
What to expect after the procedure:
1. The procedure takes from ½ hour to 3 hours. You will receive “conscious sedation” for relaxation and comfort.
2. You will need to lie flat for two to six hours after the procedure, depending on the method used to close the puncture in your artery.
3. Typically, post embolization syndrome includes pain and fever. This is temporary. It is most severe during the first 24 hours, then it improves. Ibuprofen is recommended to treat pain and inflammation.
4. You will be discharged with medication to help with this, if you need it. Urinary symptoms may worsen for the first few days following the procedure, then will gradually improve with time. If you have severely painful urination (dysuria) after the procedure we may need to place a temporary catheter to drain the urine from your bladder.
5. Mild retropubic pain, referred to as a burning sensation for 24 hours. For patients without indwelling catheters, urethral burning during voiding is the most common symptoms after PAE, it usually last 3 to 7 days and has been treated with non-opoid and nonsteroid anti-inflammatory drugs.
6. Minimal amount of blood in stool and/or urine was reported and was self-limiting.
7. In the Portugal group, approximately 10% had prostate re-growth, and needed re-treatment within 2.5 years.
These are uncommon complications of prostate embolization, but we need to mention them:,
1. Of angiography: rarely there are complications related to the puncture site, the use of a contrast agent or radiation injury
2. Pelvic Infection –any time the body is entered, there is the chance to cause infection
3. Ischemic Complication – cutting off the blood supply to other tissues, such as the bladder or rectum.
4. Sexual Dysfunction – if you had erectile difficulty prior to procedure, it might not improve
5. Nonprostatic embolization (bladder, rectum, genitals) -- the embolic particles go somewhere other than the prostate. This is less likely when the interventional radiologist injects the embolic particles by hand, rather than by using a power injector; and less likely when cone-beam CT technology is available in the angiography suite and is used to plan the injection.
6. Adverse drug reaction – allergy or sensitivity to a medication
7. Pulmonary Embolism – blood clot travelling to a lung
Comments please!