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Low Calcium

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Posted 10/24/2015 4:21 PM (GMT 0)
My dad was on Xgeva for over a year but suddenly calcium levels dropped to dangerous levels. He has been getting IV infusions of calcium gluconate and has increased calcium supplements significantly but levels rise but then fall again. Anybody experience this? He is also on Xtandi. Was admitted to hospital and even the Endochronologist Team couldnt figure out where the calcium was going. It is not in his urine either. Anybody have any idea?
Posted 10/25/2015 1:40 AM (GMT 0)
Welcome to HW.

That's not something I hear a lot about. Hopefully some of the advanced treatment folks will be along to help with an answer.

Andrew
Posted 10/25/2015 2:55 AM (GMT 0)
I'm sure his endocrinologist looked at all this - What are his serum Vitamin D levels doing? Is he taking Vitamin D with the calcium supplements? What is his parathyroid hormone level? Vitamin D binding protein? Vitamin D Receptor status? CYP27A1 level? Is he taking any supplements with magnesium (milk of magnesia, antacids or laxatives with magnesium)? He's not on Xofigo, right?

I hope they discover the cause soon.

- Allen
Posted 10/25/2015 11:56 AM (GMT 0)
Tall Allan - thank you... yes all of those essential levels have been checked He is not on Xofigo. They seem to think that over time xgeva does this... usually his diagnosis would come with high levels of calcium so it is a mystery. Thank you again for taking time to respond.
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