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Strange fluctuating PSA???

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Posted 10/30/2019 1:11 AM (GMT 0)
Has anyone had this happen?

My PSA became detectable in June 2016, 3 years after my RP. See my signature. We've been watching, and I've been trying cbd/thc. I was due my 4 month test last week. It came in at a whopping 3.3, nearly 10 times the previous test in June. My doctor and I thought woah! maybe that's a mistake? So he ordered another test today, and it came back at 1.2, in less than 6 days. Now I'm wondering whats going on?

Has anyone had this happen? I wonder now, does it fluctuate like that between test? and I've just been lucky in my test timing??? Heck, it went undetectable for nearly 2 years shortly after the first detectable, I can't find a thing online anywhere, only references to doubling time.

I have messaged my team at MDA, and waiting hear back.

I just wondered if I'm the only one that this has happened too???
Posted 10/30/2019 1:28 AM (GMT 0)
Your PSA tests have been quite unusual since 2016. I have no idea what may be going on. I was thinking your most recent tests would indicate a recurrence, but the retest is puzzling. Only thing I can think to do is yet another retest.
Posted 10/30/2019 10:45 AM (GMT 0)
I need to revisit my CBD/THC thread. The THC does not agree with me, so I have abstained from that since last year. After the test came back at 3.3, I took a few doses of THC oil, low and behold it dropped to 1.2? In just 6 days? That is strange. I have an appointment with a urologist at Siteman cancer center in December. I'm going to test again in about 4 weeks.
Posted 11/1/2019 1:04 PM (GMT 0)
10drum,
If you bike before test or stressed out and many other things can effect your psa.
May be it is one of thoes and I don't know all posible things that have an effect on psa.

I fast the night before and get mine checked early (7:30) in the morning and it seems to be lower.
I use to go to the Mays building at MD Anderson the last time was seen 2016. Mostly I'm seen in Tulsa every 3 months. When things get worse I will go back to Houston, I'm with the Subudhi clinic.
Hope it gets down even lower on your next test.
Larry E

Let me know if you think you know what lowers your score so quick.
Posted 11/7/2019 10:24 PM (GMT 0)
Larry, Thanks for the reply.
Posted 11/8/2019 12:01 AM (GMT 0)
10drum, I'd be concerned, or at least concerned, with the impact of the THC and CBD on your PSA, and your true PCa situation. Sometimes drugs can reduce PSA, but may not have a corresponding impact on PCa. Example is finasteride, which drops PSA by about 50%, but has no impact on PCa. It just makes the prostate put out less PSA. I wouldn't be confident using your PSA numbers for any decisions unless you could test again without the THC and CBD. Then, you would see your true "pure" PSA, and could make judgements about next steps, if any.

I have a similar situation, as I have been treated for PCa (CyberKnife in November 2016) but have been using TRT for many years - before diagnosis, during and after treatment. When my T goes up a bit, so goes my PSA. As long as the excursions are minor, we just write it off as "noise" but if anything went seriously out of range, we would be forced to consider stopping the T to get a new "normal" reading.

Not trying to tell you what to do. Just bringing up a similar situation for your information.
Posted 11/11/2019 7:40 PM (GMT 0)
Paxton,

Thanks for your reply. You said, "Sometimes drugs can reduce PSA, but may not have a corresponding impact on PCa"

I've wondered the same about ADT, does it counter act the PCa, or just cause your body to produce less PSA???

The way I understand how ADT works, is by lowering your testosterone. I think PCa may be fed by testosterone?? THC has been proven to lower testosterone as well.

I really don't know. I am hoping that the 3.3 and corresponding 1.2 are just "noise". As for testing without THC/CBD, I had not taken any THC/CBD for nearly two months prior to the 3.3 test, prior to that I was only using a very high CBD/ low THC supplement. I'm on the real deal now, 1:1, THC:CBD. I may be getting use to it. The people at the dispensary have been telling me I need to take more, but they are dealers, so of course thats what they're going to recommend.

Thanks again for the reply.

Phil
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