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Any documented cases of post RP uPSA rising and then plateauing indefinitely at a low level?

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Posted 1/10/2020 7:43 AM (GMT 0)
Also been posting on how Tumeric likely falsely lowers upsa test results while biotin, vitamin b7 like falsely raises upsa results. No supplements like these for at least 72 hours prior to upsa testing. I learned this the hard way. They have no impact on cancer just masking or falsifying upsa levels.

more studies about PAINS" - Pan Assay Interference Compounds

Curcumin May (Not) Defy Science

https://pubs.acs.org/doi/full/10.1021/acsmedchemlett.7b00139

The Essential Medicinal Chemistry of Curcumin

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00975
Posted 1/10/2020 8:34 AM (GMT 0)

jronne said...
Also been posting on how Tumeric likely falsely lowers upsa test results while biotin, vitamin b7 like falsely raises upsa results. No supplements like these for at least 72 hours prior to upsa testing. I learned this the hard way. They have no impact on cancer just masking or falsifying upsa levels.

Now, I'm worried. I hadn't heard of this before. I take a herbal pill that includes cucomin as an anti-inflammatory for joint pain.
On the bottle it says each capsule, curcomin c3 complex 200mg from tumeric rhizome 13g standardised to curcuminoids 190mg with some other stuff (black pepper, boswellia and ginger)

I only take the one pill so no idea if this dose is considered too low to affect psa ??
Posted 1/10/2020 1:34 PM (GMT 0)
Jeesh, I wonder if they will come out with a PSA test that measures out to four digits? 😉
Posted 1/10/2020 4:28 PM (GMT 0)

mattam said...
Jeesh, I wonder if they will come out with a PSA test that measures out to four digits? 😉

LOL

Sometimes I think the degree of obsessing about PCa is inversely proportional to the severity of the disease. Odd.
Posted 1/10/2020 4:33 PM (GMT 0)
A < sign and two numbers is more than enough for me!
Posted 1/10/2020 8:13 PM (GMT 0)
See a recent post for a relevant response:
https://www.healingwell.com/community/default.aspx?f=35&m=4176716
Posted 1/11/2020 12:14 AM (GMT 0)

garyi said...

LOL
Sometimes I think the degree of obsessing about PCa is inversely proportional to the severity of the disease. Odd.


I don't care what others think.
Knowing whether I'm 0.035 instead of 0.03 is important to me. 0.05 will likely be my trigger point for radiation and that 0.005 on an ultrasensitive test, while insignificant or meaningless for you is important to me.
Posted 1/11/2020 3:26 AM (GMT 0)
the key is that there is a natural variation in PSA levels, at some point, there is a diminishing return to additional uPSA accuracy

down to the low 1000's is the proper level of diminishing return in my opinion

the advantage is an early warning and trend analysis as the underlying uPSA noise averages out with time and additional data points

basic science and statistics apply, really not that hard to comprehend or appreciate
Posted 1/11/2020 3:33 AM (GMT 0)
hey jasperx10, it was ****ing news to me too

I still cannot get anyone to advise how many days one must avoid Curcumin to get a valid uPSA test that is not artificially low

more studies about PAINS" - Pan Assay Interference Compounds

Curcumin May (Not) Defy Science

https://pubs.acs.org/doi/full/10.1021/acsmedchemlett.7b00139

The Essential Medicinal Chemistry of Curcumin

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00975
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