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Posted 3/11/2020 1:10 AM (GMT 0)
Hi Folks,

Finished SRT in October and 6 months of ADT (Lupron plus Casodex) would have run its 6 month course in November. I know there is a half life to the Lupron/Casodex stuff but I am feeling the effects more now than during what I remember the actual treatment period feeling like. I was able to keep my exercise routine throughout treatment but things have been going south since. I run and exercise religiously but my pace and distance possibilities have diminished very, very significantly since treatment was officially “over”. Is this to be expected? Have others felt this kind of decline post treatment? Also just feel more run down and have less motivation than usual.
Posted 3/11/2020 1:17 AM (GMT 0)
I was on ADT for three years and had similar diminished ability. Once your T recovers so will you. It will take several months, just keep at it. Have you had your T tested? Half life of Lupron is about 6 months and is effective so long as about 10-15% is still in the system. Expect 6-12 months after your last shot until T regains normal range.
Posted 3/11/2020 1:29 AM (GMT 0)
Thank you JNF. Appreciate the response. T was 49 in December. I will keep up the regimen.
Posted 3/11/2020 1:43 AM (GMT 0)
As an addendum, I guess the thing that has me perplexed is that I feel worse post treatment than during. I was hoping T rising would move things in the other direction. Anyone have that experience?
Posted 3/11/2020 7:10 AM (GMT 0)
Yes, AJ, same for me. Lingering ADH issues for months after treatment. Then things get better.

For me -- maybe similar to you -- after nearly 2 years of continuous preoccupation with PCa -- initial dx followed by tx decision, surgery, recovery, persistent PSA leading to another tx decision, salvage RO and a year of ADH -- I was psychologically exhausted. Which creates a sort of physical exhaustion. You get used to PCa being on the frontburner and suddenly it's on the backburner. I dunno. Took me a while to get used to.

Anyway, hope that helps.
Posted 3/11/2020 4:14 PM (GMT 0)
I have had a slight reduction in how many reps and weights I can handle, and running stamina is down a bit. I too, run and exercise regularly with some diminished performance. almost two years since SRT + Lupron and Casodex were over. Lingering effects or getting older....who knows, but I ain't stopping.

uPSA is 0.074 and T is 398, with free T low, at 4.8......and the beat goes on.
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