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From CDC: COVID vaccine priority recommendations: who gets it first

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Posted 1/13/2021 2:18 PM (GMT 0)
It does appear that how it all works is extremely local. For example, in PA, it's being handled by the county health departments, so here in Bucks, they are still in 1A (health care workers, nursing homes, etc). In other counties, they have moved into later stages. I've seen signs at Walgreen and CVS basically telling us to be patient, they will have it eventually.

It does appear to me that the jurisdictions which were better about the earlier stages of response by pushing the shut downs and mask rules etc. (and where people were better about compliance) are also doing better on the distribution side.
Posted 1/13/2021 2:58 PM (GMT 0)
FYI from MN DOH through 1/9/21

Doses promised from CDC: 541,000
Doses shipped to MN providers: 329,000
Doses shipped for CDC long term care: 101,000

Total doses promised from CDC: Number of doses that the federal government has allocated to the state of Minnesota, including doses for the CDC’s Pharmacy Partnership Program for vaccination in long-term care settings. This number updates weekly and does not include doses that the CDC has allocated directly to federal organizations in Minnesota (like Veteran’s Affairs, Indian Health Services, Bureau of Prisons, and the Department of Defense). Federal agencies and other national partners receive COVID-19 vaccine doses that are not shown in our data, because the federal government is responsible for allocating doses to these agencies. At this time, we do not know how many COVID-19 vaccine doses they may have received. As a result, the current number of doses promised to Minnesota may be an undercount of the total doses actually coming to the state.

Doses shipped to Minnesota providers: Number of doses that have been shipped to providers in Minnesota from the federal government’s allocation for the state. This does not include doses that have been set aside for the CDC’s Pharmacy Partnership Program for vaccination in long-term care settings. This is a cumulative count of COVID-19 vaccine doses recorded as shipped to Minnesota providers in the Centers for Disease Control and Prevention’s (CDC) Vaccine Tracking System (VTrckS) since Dec. 13, 2020.

Doses shipped for CDC long-term care vaccination program: Doses from the federal allocation for Minnesota that are shipped to pharmacies participating in the CDC’s Pharmacy Partnership Program for vaccination in long-term care settings. Doses for CDC’s long-term care vaccination program (also known as the Pharmacy Partnership Program or PPP) is a cumulative count of COVID-19 vaccine doses that have been transferred out of the state allocation to the federal Pharmacy Partnership Program. These doses are shipped to three large pharmacy chains, CVS, Walgreens, and Thrifty White, who vaccinate staff and residents within long-term care facilities.

The majority of the vaccinations administered have been by hospitals to 18 - 49 year old females as of last Friday. All I can tell from this jumble of data is that the state is following the original distribution plan, not getting all the dose promised, and running about 36% vaccination rate of doses delivered. Widespread distribution has not occurred yet here as healthcare and nursing home are getting the majority of doses delivered.
Posted 1/13/2021 3:31 PM (GMT 0)
I'm getting my first shot as a 75+ this friday...the conversation about efficacy due to age is an interesting one...as in all things of the body...if I may paraphrase a political statement routinely use in elections of the past...'it's the biology...stupid'...there is a parallel effect in the efficacy due to the soul I am sure...umm what to call it?...Ok...a shot in the dark?...neigh...OK I got it..."a horse with no name">>>>>>>>>>>>now there is the dimensional rhyme of which I Harp...but then...I am deep into the novel The Idiot...and the spiritual epilepsy that results from my well...from my Biology...DANG...why do I see "lo" in so much that I read and right...turn unto...and LO..."tis a puzzlement"...deliciously lo... PS digressions are not a sin...they are petals that roam eternity searching for fragrance gone...
Posted 1/13/2021 4:44 PM (GMT 0)

Pratoman said...
[
Paul, from what i read, i believe on the Moderna website (i will try to find it and post later if i do), .....
overall effectiveness for Moderna was 94.1%
Efficacy for under age 65 was 96%
Efficacy for age 65 + was 85%. This group was 25% of the cohort of the phase 3 trials

Prato, I just reviewed the FDA Briefing Document (12/17/20) on the Moderna vaccine and your numbers are very close. The final efficacy analysis showed:
Overall: 94.1%
Age 18 - 65: 95.6%
Age 65+: 86.4%

The other good news from the final efficacy analysis was that there were ZERO "severe" COVID cases in the trial...in any age group. So while us old folks may not be totally immune to the virus there is a great chance that even if we get it post-vaccine we will not get dangerously ill.

Jim
Posted 1/13/2021 10:20 PM (GMT 0)

Tudpock18 said...

Prato, I just reviewed the FDA Briefing Document (12/17/20) on the Moderna vaccine and your numbers are very close. The final efficacy analysis showed:
Overall: 94.1%
Age 18 - 65: 95.6%
Age 65+: 86.4%

The other good news from the final efficacy analysis was that there were ZERO "severe" COVID cases in the trial...in any age group. So while us old folks may not be totally immune to the virus there is a great chance that even if we get it post-vaccine we will not get dangerously ill.

Jim

Yes, i read that. Which was really good news.
Posted 1/13/2021 10:29 PM (GMT 0)
My wife had her 2nd Pfizer shot today. Sore arm - her co-workers did have some side effects - slight fever or cough for a few days.

I'm still waiting as I'm working from home anyway - something about the whole thing is strange to me - but that is just me.

JNJ - big here in NJ (as is Pfizer) is coming out with one too
Posted 1/14/2021 6:58 PM (GMT 0)
The temporary emergency approval granted by the FDA for both Moderna and Pfizer are for two doses to be given about 2-3 weeks apart. There were numerous reports that the effectiveness of a single dose was too low for the FDA to grant the emergency approval. If it turns out many people can’t get the second dose in a timely matter there could be FDA problems with those two vaccines.

I understand the J&J vaccine in Phase 3 is a single dose and early reports are that it’s effectiveness is in the mid 90% range and they expect to apply for emergency approval within a month or so.
Posted 1/14/2021 8:38 PM (GMT 0)
Based on the trials, Moderna second dose is to be given 28 days after first dose. Pfizer, 21 days. I have an appointment locked in for the second dose, they gave it to me at the vaccination site when i got my first dose.

NYC Mayor just said that the city will run out of doses in 2 weeks based on current projections. So i dunno what happens to those who just got their first dose.

There is debate about the time one can wait and still have effective eficacy with a delayed second shot. But most agree that if the delay is 4-5 days, its not a big deal.
Posted 1/15/2021 4:07 AM (GMT 0)


Had this quiet revelation this evening, as I was mulling things over ...

If efficacy was equivalent among all vaccines, it's too bad the one-dose vaccines weren't the very first ones out of the gate ...

Just wishful thinking ...

"One & done" - - - would help speed the plow ...

C-Y-C-L-O-N-E ~~~ # Iowa State University
Posted 1/15/2021 7:45 AM (GMT 0)
Got my initial Modera Vaccine shot today at China Lake Naval Base, because I am termed an essential worker (contractor). Also I am 65 and immune compromised. They instructed me to return in 28 days, hopefully they will have doses at that time. They gave out 100 shots today, about 4,000 workers here, Navy personnel and contractors rebuilding the base.
On the other hand, got a call from an old friend, just he just was admitted to the Hospital in Pasadena with a bad cough and tested positive for Covid. .
Wings over the Vaccine
Posted 1/15/2021 12:58 PM (GMT 0)
The Johnson and Johnson vaccine is also stable at typical refrigeration temps for three months. Good news for many more places in the world that do not have the infrastructure to support the extreme cold required of the currently approved Pfizer vaccine.

J&J says they can produce a billion doses in 2021.

The early bird may catch the worm....but the second mouse gets the cheese.
Posted 1/15/2021 8:11 PM (GMT 0)
Couple of not so good items for the world today

Johnson & Johnson (JNJ) expects to release results from its vaccine trial in about two weeks, but manufacturing issues will delay distribution of the vaccine until April.

The Chinese vaccine CoronaVac, made by Sinovac, showed only 50% effectiveness in a trial in Brazil, not the 78%+ that had been initially reported by Brazil’s Butantan Institute.
Posted 1/15/2021 9:45 PM (GMT 0)
I see Johnson & Johnson is also studying a two-shot vaccine.

https://www.jnj.com/innovation/questions-about-johnson-johnson-investigational-covid-19-vaccine
Posted 1/16/2021 3:12 PM (GMT 0)
https://www.bloombergquint.com/onweb/norway-warns-of-vaccination-risks-for-sick-patients-over-80

For those possibly very old it might be best to check with their dr first.
Posted 1/16/2021 10:22 PM (GMT 0)
Live link

https:///www.bloombergquint.com/onweb/norway-warns-of-vaccination-risks-for-sick-patients-over-80
Posted 1/17/2021 6:13 PM (GMT 0)

Schools in my area --- for miles around ---- were closed on Friday for a "Snow Day" ---

In my neck of the woods, in the north-central Midwest, we have had three major snowstorms in the past three weeks ... which then evolved into blizzard warnings for drivers.

The news here focused on the delivery of the vaccines to designated distribution centers during these winter storms --- and the tracking of the vaccine delivery trucks during these storms.

The news also featured how these winter snowstorms have impacted the inability of citizens to receive vaccines during these snowstorms and blizzards ---- and the necessity of closing vaccination sites, due to winter weather events.

Just another aspect to the vaccination efforts in this part of the country!

Snowplow drivers --- DEFINITELY essential workers !
C-Y-C-L-O-N-E ---- # Iowa State University
Posted 1/17/2021 6:23 PM (GMT 0)
Funny but true. In our area, our usually very reliable ISP was down for the day, resulting in school cancellations (virtual learning). A common new phrase here is that ISP down = the new snow day!

Mel
Posted 1/17/2021 7:43 PM (GMT 0)
Where I live (Bucks County PA), the health department has opened a sign up on their website for group 1B, and both my wife (educator) and I (critical manufacturing) have signed up. We'll see what happens next.
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