There are 18 variants (types) of PCa-link to web information

In case people thought there was only one type, the prognosis for some of this variants which can be rare cases, can be bleak in comparison to what most of us face. Good pathology should be able to define which type you have, another reason for possible reviews by experts (Bostwick, Epstein, Oppenheimer etc.)

I have seen a few people who got diagnosed with small cell PCa, it is so sad I won't talk about right now.

Link:  www.webpathology.com/case.asp?case=23  

Kind of gives you a better perspective cause it shows photo/slides of what pathologists look at, it is an art to define, what, where- like as to perineural invasions, Gleason scoring, percentages found etc.

Interesting to know even a little on this stuff.

zufus-Bob

Hi Tony and congrat on moderator status, I didn't know about the scarcoma of the prostate cases, I have heard that some very aggresive PCa's (high end Gleasons no doubt included) can give off little or no PSA's, so another exception to the PSA monitoring can exist and this one would be scary to find out the hard way about where you stand with PCa in your body, this is why other markers are needed. Folks that are very high risk, high stats, should be under the care of oncology doctors and not uro-docs because of level of expertise that could make a difference to you the patient.