Google the abstract and information on 'Bolla Study' it did show that patients did fare better or longer in this study and seems to have value, how much, how perfectly, look for yourself. As primary treatment I did the concept of Bolla study with neo-adjuvant ADT3 5-6 months before radiations, and ADT after radiations (total of 2 yrs.), then switched to different drug used intermittently thereafter (which I posted on a number of times). If you look at Bolla results, they are impressive differences....one has to weigh the trade offs and decide for yourself. You could consider various other drugs in doing similar works(discuss with oncologists if you are curious), uros all push Lupron and their equivalents, they don't prescribe other choices, some onco docs do.
Based upon my original stats and total urinary blockage from PCa (bad stats), I believe this protocol and the specialized radiations helped me to get this many years, thus far (8 yrs.+). Also, quality of life is especially decent after getting off of ADT drugs, thereafter.
Weigh everything is probably a good idea.