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Reasonable time to re-biopsy

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Prostate Cancer
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Posted 5/9/2010 1:49 AM (GMT 0)
Last November I was diagnosed with a low grade/low volume PCa. It was less than 1% of 1 of 12 samples.

The biospy was done after my PSA went from 1.3 to 3.0 in an 8 month span. The biopsy was double checked and accurate. My choice: Active surveillance or surgery. Radiation not recommended (I am 55 yrs old).

I was set for surgery in March - but first asked for another PSA test. Well, I was blown away when it went from 3.0 to 1.67.

So there I was with low grade/low volume and a declining PSA. I decided to wait on the surgery. My Uro agreed - but recommended a re-biopsy to be sure it's as minimal as we first found. (This was in no small part due to the fact that I am on a low dose HRT that keeps my T level at @ 300. Everybody gets very nervous about testosterone supplement with PCa).

I am now 6 months from the first biopsy. Please, are there any opinions on how soon or how frequently to re-biopsy.

Thanks in advance.
Posted 5/9/2010 3:12 AM (GMT 0)
Hi and welcome to HW. My first biopsy was in August, and I had a confirmatory biopsy (to see if active surveillance was appropriate) about 8 weeks later (which was sufficient time according to my uro). Unfortunately, the second biopsy showed more cancer than the first, and I opted for treatment. My body seemed to fully recover from a biopsy in about three weeks - no more blood in semen by that time. Your biopsy results showed less tumor than mine, and the drop in PSA is encouraging - mine did not really do that.
Posted 5/9/2010 3:54 AM (GMT 0)
I had a biopsy about 6 weeks after a biopsy and had no problems. I would suggest a color doppler ultrasound guided biopsy. I think it would be very difficult to hit that spot again and a color doppler will give a good baseline if you continue on AS.
JohnT
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