Mine told me that they work against each other
1) Trimix works by being absorbed by the cells in the 2 Corpus Cavernosa chambers , the longer the medication stays in those cells the longer they are able to work. The bodies blood flow will clear out the medication and the erection will subside
2) Any of the 3 ED oral medications work on the principal of increasing blood flow to the penis.
So taking any ED pill will result in the Trimix being flushed out faster.
Once I tried my Trimix shot approx 12 hours after taking a Cialis and my erection "only" lasted 20-30 minutes and not quite as hard as when there was no Cialis the day prior. Without any ED oral meds Trimix works for a 1.5 hr erection every time
Note: The same goes for L-Arginine, it also increases blood flow (Nitric Oxide) which while great when taking oral ED works against Trimix
Its pretty well documented that any of the 3 oral ED drugs lowers BP, it was not likely the Trimix
www.webmd.com/erectile-dysfunction/cialis-viagra-levitra-treat-ed