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Bayer Prostate Cancer Drug Cuts Death Risk by 30%, Study Shows

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Posted 10/4/2011 8:30 PM (GMT 0)
 

http://www.bloomberg.com/news/2011-09-23/bayer-prostate-cancer-drug-cuts-death-risk-by-30-study-shows.html

Saw this thought I pass along...

Posted 10/4/2011 8:39 PM (GMT 0)
Shu93

Thanks!

This is the third or fourth drug I have seen recently (on HW) that are looking very promising for PCa.

Moderator Types - Would it make sense to have a drug in the pipeline sticky ?

Bud
Posted 10/4/2011 9:31 PM (GMT 0)
SHU, thanks for the post.

Every time a new drug is mentioned here, I always go take a look. With my rising PSA it is certainly of interest to me.

But once again I was somewhat disappointed to see that it is yet another drug that is used for hormone/castration resistant PCa.

Sure wish someone would work on a drug that attacks the PCa before you have to go through HT and get to the point of refractory. We are all aware that HT is not curative and refractory is almost always something that will occur.

Maybe one day, but that day doesn't seem to be too close yet.

Thanks for the info,

Sonny
Posted 10/4/2011 10:02 PM (GMT 0)
Mary here,

I'd like to see a link to the science that says the 'death rate' is 30% lower.

Do they mean that 'healthy', productive men with mets will have a longer life or just those who are already ravaged by the cancer?

To Willie and I, those are two different populations and should be differentiated from one another.

If anyone knows how to find the double blinded study for this, we'd love to have a link.

Thankyou and stay well.

** I did find some information about this drug on the internet and nothing was said about Quality of Life issues, just about adding approx. 2.8 months of life and a possible delay of bone met activity.

Post Edited (Willie B) : 10/4/2011 4:30:54 PM (GMT-6)

Posted 10/4/2011 10:44 PM (GMT 0)
Mary, try this link. It has some really good info and an interview with the lead dr on the trial.

biotechstrategyblog.com/2011/10/radium-223-alpharadin-in-advanced-prostate-cancer-an-interview-with-dr-chris-parker.html/

Sonny
Posted 10/5/2011 1:04 AM (GMT 0)
Thanks very much Sonny for the link.

I think the sentence about 'too old, too weak or otherwise unable to.....' tells us that this drugs importance is not QOL issues but about living longer, no matter what shape you're in. Sorry about ending the sentence with a preposition.

IF, and I don't see it stated anywhere, it was used before the bone mets could take effect, it would have more value, in my modest opinion. That's where I think there's benefit.

Once the bone mets/other disease processes are underway, not so sure.

Thanks again Sonny, we have to look under every rock for advances and keep our fingers crossed.

Stay well our friends.

Mary
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