Hi Dave,
Great discussions here.
Regarding changes in your disposition, maybe you are high on iodine? I had a similar reaction when I tried juicing fresh fruits, vegetables and greens a couple of years ago. I was high as a kite, like I was drinking quarts of espresso, quit after a week, and gave my juicer away. A good friend had a similar reaction, but he was also blessed with loose bowels. He gave his juicer away too. Then last year, good friends of his in Florida who joined a juicing/detox group (sounded like a sales pyramid to me) got very sick from it and both were hospitalized. They were both in good health, and bought the hype, and it nearly killed them both.
I'm very careful with supplements. I know people tend to think they are safe because they are natural but so is arsenic and hemlock.
Yesterday I had a cup of natural tarragon tea that someone on a gardening forum said helped bph. It was about
the third or fourth time I tried it. I put two fresh sprigs (about
a dozen one inch long leaves on the two stems) in a large mug of boiling water and let it sit for 10 minutes. Last night I got up from bed 19 times to pee. (I have one of those golf clickers to keep count in the dark).
You mentioned your IPSS score improved from 8 to 7. Ouch... mine improved from 35 to 30. I've often thought my symptoms after two years of treatments were worse than most people's were when they sought treatment. My wife says it's my own fault for living with bph for 15 years, but who knows?
Regarding Nymox 1207 injections. They have been having FDA trials for NYMOX for more than a decade with all trials achieving great results. But they appear to be no closer to FDA approval then they were on day one. I wonder if it's just a giant scam to sell Nymox stock? Nymox is supposed to be a protein that eats prostate cells, thereby reducing the prostate size. People who participated in trials and posted online have claimed several years of symptom relief equivalent to taking flomax from a single round of injections. Similarly, botox injections into the prostate received great reults in European trials. Botox also kills prostate cells to reduce prostate volume. Like Nymox, a round of injections is supposed to last a year or more. But in the US and Canada, botox is approved for injections into the bladder for nervous bladder but not into the prostate.
Regarding the Thermatrix microwave therapy (also known as TUMT - Trans Urethral Microwave Therapy), I had this procedure 28 months ago. A microwave is inserted in the urethra and raises the nearby surrounding prostate tissue to 53 degrees C for about
40 minutes. It basically singes the edges of the prostate near the tube, and that prostate tissue sort of gets crispy and is supposed to slough off after a period of months. It was not painful, but the 8 weeks following the procedure were very painful. The TUMT was the first line of procedures my urologist offered, and generally doesn't last a year for anyone. While I was having the procedure done, the tech told me it wouldn't last and expect to have a Greenlight. The tech was correct. 14 months later I had the Greenlight XPS 180 watt laser, the next offer from my urologist, and had 70g. of a 120g. prostate removed. Very painful 8 week recovery, followed by 4 good months followed by 8 months of poor results again. An improvement, but from an IPSS score of 35 to 30.
Incidentally, I know the button turp and the holmium laser get better reviews in forums than the GL, but I have seen postings by people who had these "better" procedures, with essentially the same outcome as me a year post surgery.
Regarding prostate supplements, I tried a bunch and all had good effects for a few weeks, then the symptoms and retention got worse than when I started. Flomax only worked for me for a few months prior to the TUMT and the GL, and not at all after the GL.
All of the esoteric procedures help SOME people, but that doesn't mean they will help MOST people. I wouldn't be willing to travel to Manilla or Hong Kong on a chance of saving my life, never mind to improve my bph symptoms. It reminds me of all the celebrities who traveled the world in desperation to get their cancer cured, but none did. A year or so ago I saw a great documentary on spontaneous cancer remissions on people who were verified to be terminal then verified to be totally cured. One guy said after all his conventional treatments he was told he was out of options and since he was dying, he decided to drink the best liquor, smoke the best Cuban cigars, eat the tastiest food and desserts, indulge in all the pleasures and travel his money could buy. He was one of 7 people (out of millions) who had a spontaneous cure and no trace of cancer when the documentary was filmed. But I don't think wine, women, and Cuban cigars cured him. But who knows?
Regarding prostatitis, I guess I had that too. It was never diagnosed by urine tests, but after my GL surgery my urologist told me that in addition to having had the largest prostate he had ever worked on, my prostate had been "full of pus" when he was vaporizing it with the laser.
Regarding the median lobe. Mine is bigger than most prostates. I have seen it on a sonogram before and after the GL, and it is still about
a 2" x 2" 40 g. mass that protrudes completely into my lower bladder just to the right of the bladder
opening. When I cath every two weeks to keep scar tissue from the GL from obstructing the internal or external sphincter areas of the prostate, I can feel the protruding median lobe stop the cath about
an inch inside my bladder
opening. My urologist said he is afraid to take more off the median lobe for fear of puncturing my bladder with the laser.
One thing I haven't heard mentioned at all in these forums is proteinuria (protein in the urine). I have had proteinuria my whole adult life, and have also had frequency and urgency issues my whole adult life (I'm going to be 67 in a few weeks). I wonder if there's a connection?
Another thing I wonder about
is if most people's symptoms are worse at night than during the day. My main problem that led me to the GL was complete retention once or twice a night from around 3AM to 6AM, that lasted about
10 minutes after I awoke to pee. It was very painful. It was like my nerves in my bladder fell asleep and wouldn't function until I walked around and had a whiskey to loosen them up. Now I still notice my flow is much more restricted and takes longer when I wake up to pee then during the day when I am doing things.
What all of these discussions point out is that bph symptoms involve a large prostate, but reducing the prostate size won't necessarily remove all the symptoms. From that point of view, the procedure you choose, whether GL or GG, etc. are no guarantee of the level of symptom relief you will get. Like my wife says, we are getting older and none of our bodily functions are going to be what they once were. I have to keep reminding myself I'm in relatively good shape and although it's very annoying, these symptoms are not life threatening. It could be (and someday may be) so much worse.
Chicago Dave said...
Marshall:
I'll check out your PowerPoint presentation when I get a chance, but it might be a couple of days. It's good to meet so many resourceful guys on this board who are comfortable thinking "outside the box"!
If I had to treat my "BPH" again, without access to GG, I think I would start with plasma button or iodine, assuming that drugs didn't work. (My impression is that drugs eventually stop working in most guys though it might take many, many years.) I've grown quite jaded about companies that offer BPH treatments, whether medical devices, lasers or drugs.
I have not had a reason to investigate PAE therapy, so I don't know much about it. I wish that our PAE guys would report the theoretical basis in more detail. And I'm still wondering if we lost Ross.
-dave