Peyronie's from treatment

After 7 months of ADT. shingles, green light laser, brachy, and finally boost radiation, I'm trying to get life back into my leetel forgotten apendage. I was able to muster a few erections in the last few weeks, but there is a slight bend in the center that I never had and it's slightly painful.

I did some research and came up with " Peyronie's disease" Have I develop something new to add to my list?

I've been on terazosin, which is an alpha blocker, for 8 months. Any connection? or can it be from lack of use, radiation, radiation trauma? I've read beta blockers can cause this, not alpha blockers

Some causes are
Trauma
Genetics
Medications/ Vitamins/ Supplements
Other Conditions

Peyronie's disease has been associated with a number of conditions including diabetes, gout, and heart disease. Some research suggest that Peyronie's disease may be an autoimmune disorder. It has been theorized that repeated minor trauma to the tissue in penis might trigger the immune system to respond to heal the injury; however, the body is improperly responds and produces excess fibrotic tissue or fibrotic plaque.

Anyone have experience with this disease?

Hi Fauntleroy,

As you can read from my post on the link that Peter provided, my husband was successfully treated for peyronies by his ED doctor, Dr. Mulhall. Although we thought that my husband's slight curvature was caused by trimix injections, Dr. Mulhall disagreed. He said that peyronies is more common in prostate surgery patients than in the general population, but that there is no proven connection between injections and peyronies. I don't think he knows what causes it.

Dr. Mulhall said that wearing a penile extender is the first line of treatment for treating peyronies. If unsuccessful, the next line of treatment would have been injections, done at the doctor's office. I don't know what he would have injected, since my husband did not have to go that route.

My husband ordered the Fastsize extender from the owner of the company. If you are interested email me and I will get his phone number for you. My husband wore it for 2 hours a day, on the days that he did not inject with trimix (which he did twice a week). It was not painful. After about 3 months his curvature was gone.

I developed Peyronies after my surgery and it was severe. (Davinici radical prostatectomy, bilateral nerve sparring). I am relatively sure that it came from trimix and I saw Dr. Mulhall. He disagrees and feels that it just happens more often to patients who undergo surgery. I tried both traction and a series of injections from Dr. Mulhall. He injected verapamil. I did not have any improvement. Please understand I think Dr. Mulhall walks on water.

Out of desperation my surgeon sent me to another MD who prescribed a vacuum erection device. After using it for 2 months I am significantly better. I believe it is because of the VED. The next step was going to be Xiaflex which may be approved by the FDA in a month or so.

Hope this helps.

No, I didn't try it. I was very pleased with the VED. The Verapamil was supposed to be effective but wasn't as was the traction device.

Thanks
Chuck

my suspicion is that this is caused indirectly by surgery. the surgery leaves one with less than the usual erection strength. Then manipulation of the organ (use it or lose it theme) causes minor or major trauma, because you have to work harder on a softer and nerve compromised member to get results. I suspect that full erection and sensitivity protects you from injury both by requiring less activity for results and the fullness protects delicate structures from injury.

that's just my opinion.
my prescription for prevention: use Cialis or similar almost immediately, and be very careful not to overstimulate. if you must, wait 6-12 months for more healing and nerve regeneration

just my 2 cents

I have absolutely no doubt my Peyronie's disease was a result of my RP.
It developed 2.5 years after my RP went to the urologist who DX Peyronie's disease.
He said that it was common belief Peyronie's was caused by rough sex I don't believe
that for one moment in my case since my RP sex was just a memory.
If it was of rough sex before my RP well someone else was getting my share it was
not me !!!!!
English Rodger.

Since this thread has been revived I will post an update. As I posted back in August my husband completely reversed peyronies that curved to one side with a traction device. Well, how he has developed slight peyronies again but this time it curves upward. It isn't a problem but he does not want it to get worse. He will start to use the traction device again. If that does not work, there are some other good options to try posted here.

Inquisitive One:

Since you've found this thread looking for information about Peyronie's disease I should probably mention that there have been major advances in treatment for the disease in the five years since this conversation. The last post before yours today was November 2013. In December of 2013 the FDA approved a new drug called Xiaflex that is something of a game-changer for treatment of the disease. XIaflex is not without side effects and I believe it is only used for fairly severely bent cases but it does work. Something to talk to his urologist if the bending is a major problem for him.