Anyone try Xtandi for a second time?

Hi everyone,

My dad has advanced metastatic prostate cancer and is nearly at the end of his treatment options. He had an amazing response to Xtandi for about 4 months when he had his life back. Ultimately, it stopped working and his PSA rose and pain restarted. Since then he has been on XL184 with some success bone-wise but NO quality of life. He has just gone off it and we (his family) are wondering if it would be worth re-challenging him with another course of Xtandi since we still have about 6 weeks worth. Wondering if anyone has done this or heard of anyone doing it?

Thank you so much for your reply.
-Andrea

Sorry to hear Xtandi is not working for you. So strange how some meds work for some and not others. We will talk about trying Xtandi again on Tuesday. He has not tried Zytiga, but from all I read, it often doesn't work following Xtandi. Appreciate your response. Best to you.