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It's mostly good news

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Posted 12/12/2013 12:16 AM (GMT 0)
As I mentioned on another post, I recently went to Dr. John Mulhall for an initial visit to discuss ED rehab. I got more than I bargained for when he diagnosed me with Peyronie's disease and undersized testicles.

Well, further tests look like mostly good news.

1) My testicles are slightly smaller than normal. Good news: Two separate blood tests show that my testosterone level is fine so nothing to worry about here.

2) I had a sonogram of my erection (a slightly odd experience). Good news: Excellent blood flow and no venous leak, etc.

3) I had a detailed examination of my Peyronie's situation. Bad news: I have significant Peyronie's scar/plaque tissue. Good news: There is essentially no curvature of willy, because of the particular size/shape of my scar tissue. More good news: The scar/plaque is not expected to get any worse. Kinda bad news: I still need to use a penile traction device (ahem, "torture device") for the next 4 months. Good news: Traction also makes willy bigger, permanently.

4) Injections and pills pretty much stopped working for me starting about a month ago. Bad news: When I attempt to be intimate with my wife, my body apparently goes into "anxiety" mode and releases adrenaline which kills erections. (Note: I don't feel anxious, and I have no idea why this issue would have begun suddenly a month ago.) Good news: When not attempting intimacy, injections still work great, and I'm getting much better erections using pills than what I was getting a few weeks ago - so good ED progress has occurred in the last few weeks.

All things considered, I think that this is mostly good news.

-Gedman
Posted 12/12/2013 1:10 AM (GMT 0)
Very interesting report, sounds like there's an entire science to that subject. Hope things improve for you in that department.

David
Posted 12/12/2013 1:15 AM (GMT 0)
good report!

Keep it up.
Andrew
Posted 12/12/2013 1:28 AM (GMT 0)
Gedman,

You sound encouraged, which is terrific. I had no idea that there were so many facets to the mystery of ED and so many questions that need to be answered. That's the thing about this forum. You get to see so many different case perspectives on any given subject and learn of numerous questions that you would never have thought to ask. Thanks for the post.
Posted 12/12/2013 2:15 AM (GMT 0)
Gedman,
I love your positive posts and with your spirit and desire you will get it done! Also wanted you to know that I'm sure that your links are very helpful to "newbees". You are "paying it forward" IAW Yoop's manta..All the best to you!
Bull idea
Posted 12/12/2013 2:48 AM (GMT 0)
I sound positive/hopeful now, because I was fortunate to have a good outcome from today's tests with Dr. Mulhall.

I chose not to post about this topic during the last few weeks while I was a bit dark/moody due to my fear that Peyronie's plus the sudden failure of injections/pills could mean that I'd never get an erection again (unless I got surgical implants).

-Gedman
Posted 12/12/2013 4:19 AM (GMT 0)
thank you for the detailed update on your penis cool
Posted 12/12/2013 5:09 AM (GMT 0)
Great news - especially that there is no venous leak!

For the Peyronie's -- On Friday, the FDA approved a new injectable drug that dissolves the plaque called collagenase clostridium histolyticum (CCH, Xiaflex). It may be easier than the penile traction, but there is usually a wait between FDA approval and its appearance on the market. Maybe you can call Mulhall's office and ask him to call Xiaflex. They may want to get him on their side by giving him a sample.

The article said...
According to the FDA, CCH will be available only through a Risk Evaluation and Mitigation Strategy (REMS), a stipulation the FDA places on approved therapies when a risk of potentially serious adverse effects exists, in this case, penile fracture and other serious injuries to the penis. The REMS for CCH requires healthcare professionals to complete a training program for administration of CCH to patients with Peyronie's disease.

Clinical data to back up the application for a new indication came from a placebo-controlled trial involving 832 men enrolled at 54 centers in the U.S. and 10 in Australia. Eligibility criteria included penile curvature of 30-90°. Men received as many as eight injections of CCH during four treatment sessions, and follow-up continued for a year. The results showed that CCH led to significant reductions in penile curvature as compared with placebo.

During the first follow-up after the initial injection session, patients receive instruction in stretching the penis as an adjunct to CCH. For the most part, men have practiced the manual manipulation, and the occasional patient who has not remained adherent has had less improvement in the condition as compared with men who practiced the stretching exercises.

Despite the REMS requirement attached to the approval, serious adverse events have been uncommon, he added. The most frequent adverse reaction has been bruising and swelling at the injection site, effects that usually resolve within a few days.

- Allen
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