Surgeons always operate from one side of the patient. They make an incision on one side and start cutting the prostate capsule away from its fossa from that side. Then they reach across the prostate to cut away the rest of it. This seems to lead to a better quality of dissection on the incision side compared to the other side. What this study indicates is that the point of view they have while dissecting makes a difference in the oncological outcome of the surgery.
They suggest a bilateral approach instead - starting the dissection from an incision on one side, and then flipping to the other side to complete the dissection. There will always be positive surgical margins because sometimes the tumor has already penetrated into surrounding tissue (T3a), but if they're right, this change in technique would greatly reduce the number of positive margins - up to 59% of them - caused by not adequately cutting the prostate away ("iatrogenic").
So if you're going under the knife soon, show this to your surgeon.
Wrong to be Right: Margin Laterality is an Independent Predictor of Biochemical Failure After Radical Prostatectomy.- Allen