"Focally present" at margin

J, focal usually means length of 3 mm or less
It may be important to know the G score at margin.
Here is the link for good review which may be helpful:
http://www.harvardprostateknowledge.org/positive-surgical-margins-following-radical-prostatectomy

I am wondering if your Uro suggested seeing RO given the fact you have G 4+3, both EPE and margin...so RT maybe a consideration.

Mos

Until your PSA gets to .01, all you have is an interesting pathology report.

If your surgeon cut wide enough the margin you're worried about could be in the path lab and not your body...

just say'n

Andrew

Mos_Ser said...
J, focal usually means length of 3 mm or less
It may be important to know the G score at margin.
Here is the link for good review which may be helpful:
http://www.harvardprostateknowledge.org/positive-surgical-margins-following-radical-prostatectomy

I am wondering if your Uro suggested seeing RO given the fact you have G 4+3, both EPE and margin...so RT maybe a consideration.

Mos

This interview was 2009. At that time, .1 was considered detectible. Therefore, that's the number around which these Drs. are talking. It's interesting....to know whether any of these people's minds have changed in the last 7 years. Might be worth a call....maybe a phone consult.

I'm just thinking LOL ahead. lol this much I do know. and it 's all , the only thing I (think I) know. lol Radiation ain't happenin' on 'Ol Rocky Top for this hombre. It's takes some expertise for this.

great (useful) article Mos_Ser.

Jay -

Harvard Medical School -

"What’s the significance of focal positivity?

GENEGA: In the pathology report, I’ll say that there is “margin positivity.” The urologists will then want to know the extent of the margin positivity. Is it unifocal, meaning a single positive margin or single area, or is it multifocal? That’s usually on the report, but they sometimes want to know how large the involved area is. Is it a 2-millimeter area or a large, 5-millimeter area?

WAGNER: I think it’s important for patients to know that information. A few studies have looked at the prognosis for patients who’ve had a focal, or single, positive margin versus those with multiple positive margins. I don’t think everyone agrees, but at least one published report says that the chance of recurrence is greater with multiple positive margins. An abstract of a study on this question was presented at the 2008 American Urology Association [AUA] meeting by researchers from the University of Michigan. They looked at the risk of recurrence with extensive positive margins compared with focal margins in their T2 patients — that is, patients whose cancer was confined to the prostate. They found that the patients with extensive positive margins had a 45% risk of recurrence at 10 years compared with a 15% risk of recurrence for the patients with a focal margin."


look here -

www.harvardprostateknowledge.org/positive-surgical-margins-following-radical-prostatectomy

Bobby Mac

Bolo, Looks like EPE was neg on MRI, but pos on surgery pathology.

Chas