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PET SCANS

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Posted 12/15/2016 1:24 AM (GMT 0)
G 4+3, unfavorable
Posted 12/15/2016 12:40 PM (GMT 0)
Added the signature
Posted 12/15/2016 5:58 PM (GMT 0)
Ah - so all of you fell into the unfavorable intermediate risk category.
Posted 12/23/2016 12:54 AM (GMT 0)
Everyone is different, but just as a FYI...I've had the #2 and the #7 scan on the list at the same time and the #7 found a bone met that the #2 did not. In fact, had the same two scans 6 months later and the #2 scan never picked it up.

Great write up Allen.

1. F18-DCFPyL
2. F18-DCFBC
3. Ga68-PSMA-HBED-CC (Ga68-PSMA-11)
4. (F18 - FACBC)/ Axumin
5. C11-Choline/ C-11-Acetate
6. F18-Choline
7. NaF18
8. F18-FDG
Posted 12/23/2016 1:14 AM (GMT 0)
Jerry,

You're raising a very good point. 95% of prostate cancer mets may express PSMA to varying degrees, while 5% do not. The first 3 on the list are PSMA scans. Their high detection rate may be attributable to the fact that many early metastases are in lymph nodes. The NaF18 PET is specific to bone, and is useless for soft tissue mets. It should get picked up by all "blastic" bone mets, and most PC bone mets are blastic.

The one on the bottom of the list, FDG, may actually be the best one for detecting the most advanced metastases. I put it on the bottom because most guys with mets want to get their first PET scan at an earlier stage, and by the time that an FDG PET can detect it, a bone scan/CT can probably detect it too.

The non-PSMA PET scans now being tested may be more sensitive and specific.
Posted 12/23/2016 3:23 AM (GMT 0)
Allen,

Awhile back I had a biopsy done on that spot and sent a specimen to the NIH, where I had the scans. They were going to see if it tested positive for PSMA. I forgot to follow up with them to know the results.
Posted 12/23/2016 3:26 AM (GMT 0)
With the new PSMA-targeting radiologicals, that could be useful to know.
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