Pca Screening/Diagnostic Tests

Hi Everyone,

Note that I have not yet had Biopsy but am scheduled for later in April. Considering the tests I have had indicate high Pca probability.

This is my first post. I have been reading and learning a lot on this forum for about 3 months and so now I just joined and hope to get some feedback. I am 61 yo and generally good health. I had a physical Nov 28, 2016 hoping all tests would be fine and I would retire - but only PSA was out of line - a little high at 6.6. I decided to delay retirement to checkout further the high PSA result. From there I had PSA repeat Dec 29, 2016 which is 6.7 with free PSA of 11%. My DRE suspicious from 2 different Urologists. They want to proceed to Biopsy.
Previous PSA tests were June 2008 at 1.6, May 2006 at 0.95, and Sept 2003 at 0.5.

I resisted immediate Biopsy and changed Urologist and had Pca3 test high at 116 ( < 25 "normal") with DRE suspicious. Urologist agreed at my request to do 3TMRI before Biopsy.

My request is if you can comments on My 3TMRI results. I got the radiologist report which is generally clear
but what I am hoping you can further comment on these results. My Urologist simply has not yet given any feedback other than to schedule a Biopsy which will happen later in April.

Results for the 3TMRI. Prostate volume is 63.4 ml( I think 2X average for my age). Two Lesions found and scored at PIRADS 4 =Probably Malignant. Dominant lesion is 1.5 x 1.1 cm in right posterior lateral peripheral zone at mid gland level. Additional legion found is 1.0 x 0.6 cm in left posterior zone at the level of the base.
These lesions are moderately suspicious. No evidence of extra prostatic malignancy. Seminal vesicles exhibit normal signal intensity. Neurovascular bundles are symmetric in appearance without definite tumor involvement. The prostate capsule is smooth in contour. Normal regional marrow is observed. There are general comments about the lymph nodes and region being negative or unremarkable.

Thanks for your time and comments that I may receive.

Best Regards and Cheers!
BUSMAN

There's nothing to know or do until the biopsy, I hope you can put it out of your mind until then.

My base line (first) PSA reading came back at around 4. I had done enough reading to know that was borderline. At my doc's behest (he didn't have to work hard at getting me on board with his plan) "We'll keep and eye on this". We did for 4 years. (I don't recommend this). So, I had a lot of time to research "in case it's ever needed".

I have no clue when my PSA began to rise. As mine did, yours seems to have leveled a bit. (1 month's variation of .01 is, for all intents and purposes, "no change").

After my biopsy, my MRI showed several areas of Pirads 4 and 5. Most of these turned out to be something other than cancer. So, an MRI is not the last word.

The DRE's are just more information. Your prostate is large. That could be where some of this PSA is coming from.

I agree with Advocate. Find out what's going on, if anything. Prostate cancer is generally slow growing. Don't freak. You'll know in April. Don't cancel.

edit....when I got the news....I'd done enough reading that, with my path, the cancer didn't scare me. It was the treatments that scared me. but if I can do it.....trust me....anyone can. Including you.

welcome to HW.

Yup, what you have is a good case for getting the biopsy. Until then all you have is some numbers that don't look good and a lot of uncertainty.

There are worse things than a biopsy, but you'll get through.

Do keep us updated on your results,
Andrew