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PSA after radiation treatments?
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Prostate Cancer
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weewillie131
New Member
Joined : Jul 2020
Posts : 15
Posted 9/11/2020 3:13 PM (GMT 0)
I was diagnosed Gleason 8 with perineural invasion. I have been on Lupron for 6 weeks and will begin 45 radiation treatments in a couple of weeks. What can I expect my PSA to be after treatments since my prostate will still be there? Thank you!
Sr Sailor
Veteran Member
Joined : Sep 2015
Posts : 1483
Posted 9/11/2020 5:24 PM (GMT 0)
Predicting absolute PSA values after radiation has no scientific validity. Hopefully though, it will be lower than pre-treatment and will go down as time progresses until a nadir is reached. The latter can take several years
More info would be helpful (original PSA etc.)
Cyclone-ISU
Veteran Member
Joined : Oct 2014
Posts : 3388
Posted 9/11/2020 5:37 PM (GMT 0)
Hello, Willie ---
I also had 45 radiation treatments. It's a marathon, not a sprint. Weekends give you time to rejuvenate and relax.
We're here to encourage you, along the way!
Some radiologists don't run PSA tests during treatments, because they can roller coaster, up and down, which can be needlessly discouraging.
After treatments finish up, it can take a while for PSA levels to "settle down" ...
My series of radiation treatments really helped me ---- each treatment counts, and "counting down" the days is motivating!
With my best,
CYCLONE - # Iowa State University
JNF
Veteran Member
Joined : Dec 2010
Posts : 5986
Posted 9/11/2020 7:12 PM (GMT 0)
Since you are on ADT it will push your PSA to undetectable very quickly and should stay there while you are on ADT anD for at least three months after your last shot has worn off.
I had ADT and radiation. My PSA went from 59 to undetectable in about
70 days or less.
Because if the ADT you will not be able to gauge the radiation effectiveness until you are off ADT and have regained a more normal testosterone level. Sr Sailor’s comments are more relevant for someone not using ADT.
How long are you planning to be on ADT? Being high risk, I would expect 18 months or so. If that is the case you really won’t know what the radiation has done for a couple of years. Most radiation men do not stay at undetectable PSA long term since they still have a prostate. But most stay at 1.0 or less. A few get to undetectable as I have and continue to be after nearly 10 years.
weewillie131
New Member
Joined : Jul 2020
Posts : 15
Posted 9/11/2020 10:12 PM (GMT 0)
Thank you for the replies.. 9 of 12 cores were 40-90% percentage cancer. No spreading so far. They told me 18-24 months on Lupron. My PSA was 26 at diagnosis with a normal DRE all along.
Post Edited (weewillie131) : 9/11/2020 4:18:50 PM (GMT-6)
JNF
Veteran Member
Joined : Dec 2010
Posts : 5986
Posted 9/11/2020 11:33 PM (GMT 0)
Thanks for the information. Based on my experience my advice for you is to relax, test PSA quarterly, trust the treatment and work on improving your overall health. Killing PCa with radiation is very effective, just a long slog. Average time to PSA Nadir is 44 months.
Do test PSA frequently to make sure the ADT is working. Also test testosterone at least every 6 months. Being on long term ADT can be tough on the bones. Get a bone density test and then one each year. Make sure your Vitamin D level is good and consider D and calcium supplements.
Exercise, diet and positive attitude will be best in managing the ADT effects of hot flashes, weight gain, fatigue and brain fog. Work your way through. Diet modifications to eliminate caffeine, carbonated and acidic drinks, less alcohol, more fresh fruits and vegetables will all help.
You are high risk, but have chosen a very effective treatment plan. Trust the treatment and do what you can to improve overall quality of life. Best wishes.
Cyclone-ISU
Veteran Member
Joined : Oct 2014
Posts : 3388
Posted 9/12/2020 1:17 AM (GMT 0)
Hello, Willie ---
Check your current thread listings on your screen ...
I just booted up a helpful thread entitled "My Experience With External Beam Radiation" started by our comrade here, TempFlightRestriction.
You will find it VERY helpful, as you begin your series of 45 radiation treatments! It will help you navigate those treatments, as weeks go by --- and best of all --- ways to mitigate side effects.
We're here for you, every step of the way! We'll start the nine-week countdown for you!
Check out that thread -- I just boosted it to the top a moment ago ---
My best,
CYCLONE --- # Iowa State University
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