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Is it possible to have a positive DRE exam and not have PC?
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AEG
Regular Member
Joined : Nov 2005
Posts : 154
Posted 6/12/2007 1:18 PM (GMT 0)
Is it possible to have a positive DRE exam and not have PC? If a Urologist feels a nodule, is it most likely PC?
AEG
bluebird
Veteran Member
Joined : May 2006
Posts : 2543
Posted 6/12/2007 7:14 PM (GMT 0)
Hi ~ AEG, I hope this helps! ~ Lee Excerpt from: “Dr. Peter Scardino's Prostate Book ” 2006 Peter T. Scardino, M.D. Chairman of the Department of Urology ant Memorial Sloan-Kettering Cancer Center and Judith Kelman Chapter 9 Page 150 The results of a digital rectal exam (DRE) are highly subjective. The same thing one doctor finds suspicious might be entirely overlooked or deemed insignificant by a different examiner. Tiny lumps or bulges may represent meaningless calcifications or benign enlargement of the glad. Only one in five abnormal DRE’s turns out to be cancer. 3 3 Catalona WJ, Richie JP, Ahmann FR, Hudson MA, et al: Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: results of a multicenter clinical trial of 6,630 men. J Urol 1994; 1283-1290. I found this link …but the percentage shows 1 in 4 http://www.prostatecancer.realage.com/content.aspx/topic/34 Excerpt from “Dr. Patrick Walsh’s Guide to Surviving Prostate Cancer”…(Give Yourself a Second Opinion) 2001 Patrick C. Walsh, M.D. Professor of Urology, The Johns Hopkins Medical Institutions and Janet Farrar Worthington Chapter 5 Page 111 PSA is prostate-specific, not cancer-specific. This is why a blood test alone isn’t enough, why a digital rectal exam is also a must. You can have prostate cancer and still have a low PSA level. And, just because you have a high PSA does not necessarily mean you have prostate cancer—many men with high PSA levels don’t. about a quarter of men who turn out to have prostate cancer have a low PSA level, less than 4 nanograms per milliliter. about 25 percent of men with a PSA between 4 and 10 turn out to have cancer.
AEG
Regular Member
Joined : Nov 2005
Posts : 154
Posted 6/13/2007 1:34 AM (GMT 0)
Hi Bluebird,
Excellent post! Thank you so much for the info.
AEG
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