yup, my dose was upped & my intervals were shortened a while ago- it worked well at the lower dose for about
9 months, then I just lost responsiveness completely. So we upped the dose to the 10mgs/kg, & I go every 6-8 weeks. I try to go every 6-what usually happens is that I have 2 bad weeks, right before & right after the infusion, then 4 ok weeks. I've noticed the duration of the med shortening though. Whatever... after this, it's Humira (if I can get it covered) or surgery.