I've been on Prednisone for 5 months now, and am currently working on my second taper (the first one didn't take). I was initially at 60 mg, and moving down to 40mg wasn't an issue. But the taper from 40mg is a little more tricky and I'm taking my time with it. Things seems to be going great so far, but I'm being very careful.
My symptoms were pretty severe so 2 weeks wouldn't have done anything for me.