I have had achy legs for a few months. I thought it was my sciatia nerve, but it is in both legs. I think it is joint and muscular. My hips to my knees ache, sometimes my ankles, and sometimes the lower left side of my left leg. I called my GI thinking it was a Humira side effect. He told me that he didn't think it was the Humira and to see my primary dr. Does Humira cause any vitamin defiencies or could it be something else? I do exercise but not enough for all this pain. Sometimes it wakes me up at night, but I have the pain during the day too. What tests should I ask my dr. for on Tues? Thanks