Question for people taking apriso

I have been on 8 capsules for almost a year now! Mesalamine is a fairly benign drug and that much (3mg) is not too much. My GI said 8 is often given to help induce remission, and 4 to sustain, even though the FDA has not outlined these doses yet. I want to get down to 4, though I'm a bit too chicken to at the moment.

The only issue you may run into is your insurance not wanting to cover that much of the meds, but my pharmacy and GI were able to work it out.

Also, be sure to get routine bloodwork--chances are you'll do totally great on the Apriso (it's been great for me) but it is a good idea to keep track of your levels in case your body is having trouble processing that much mesalamine. Plus, routine bloodwork is a good idea for us UCers in general.

Good luck!

Well keep me updated! I responded to Apriso much better than Lialda and believe the high dose with some agressive rectal treatments got me into remission.

Your GI probably wanted to see if you'd respond well to 4 at first. Also, I have a younger GI and I imagine your PA is also younger than your GI--my older GI was aghast to see I was on that much Apriso. I'm finding younger doctors are more progressive in their treatment plans, which has worked well for me.