It may be time.
I also started Pred at 40mg and was on LDN too. I think together they helped. I had a few side effects from the Pred in the beginning but nothing too bad. First it upset my tummy so I started drinking ginger tea in the AM and took it with food. My ankles would swell up during the day but went down at night. I guess my body adjusted as these went away.
The only issue I had was I was rear-ended in a car accident which affected my UC and caused me to be in the Pred longer than expected...5 weeks at 40mg! Now I seem to have problems getting off it.
I say give it a whirl starting at 40mg. Some people see results in 3 days. If you're on it for a short time you shouldn't have an issue tapering. I guess the Pred just didn't respond very well for me. It took 2 weeks to get results and the the darn car accident! Unfortunately you can't control life events...just got to roll with the punches.
Also remember it takes a coupe months for LDN to start working...if it works at all. I've been on LDN for over a year and haven't seen much of an effect from it. At least it's keeping me from going insane!
