"Indefinite for dysplasia" - anyone got this?

I had a flex sig done to check how this flare is progressing.... Anyway i got the results of the biopsy and it says that i have pretty active uc all the way from "the anal verge till the sigmoid colon"- this part was expected as thats compatible with my symptoms and location of the cramping.

However what shocked me, to put it mildly, is that the biopsies from the middle of the descending colon (above the sigmoid) ALSO showed active inflammation but less severe than in the rectosigmoid. Still though there was inflammation above the sigmoid! I thought having solid poop meant that that area was ok; guess i was wrong. My main symptoms are cramping especially right before a bm and bad urgency, as well as lots of blood (some days are worse than others).

Another shock: both specimens (the rectosigmoid biopsies and the descending colon biopsy) were marked as "INDEFINITE FOR DYSPLASIA". My GI told me that this means there were some changes in the cells but that the pathologist could not be sure if those changes were due to inflammation or due to dysplasia.

What the heck!!!!? Ive only been flaring since january and already im indefinite for dysplasia? My GI recommended i get another scope done once im in remission just to check that these cells return to normal.

Has anyone else gotten this for their biopsy? Did they return to normal after the flareup ended upon re-biopsy?

Im so scared :(

ItsAlwaysSomething said...
Low grade dysplasia was found in a tissue sample of a colonoscopy. Six months later I had another cscope with 55 tissue samples taken and no evidence of dysplasia.

So according to IAS dysplasia can be reversed at least temporarily. I concur with her advice about LDN, perhaps that was the crucial factor for the reversal.

I don't see vitamin D in your signature. Please get your blood levels checked. Check out this chart from www.grassrootshealth.net/diseasepreventionchart.pdf . It indicates that up to 60% of colon cancer can be prevented with the serum blood levels of 42 ng/ml. These are not numbers from a bunch of hippie healy-feelies but the results the most recent scientific research. Only very recently it was thought that the main function of vitamin D was only to prevent rickets. Try for blood levels at least 50-70 ng/ml.
www.grassrootshealth.net

As a side benefit vitamin D is very effective for IBD:
www.healingwell.com/community/default.aspx?f=17&m=2475161

While you are at it you can look up the research regarding folic acid and selenium preventing colon cancer. A good multivitamin can have 200 mcg of selenium which is the maximum safe daily dose.

Of course you must must must continue to monitor via colonoscopies or whatever. We are not doctors here so it may very well turn out that surgery is the best course of action.

Post Edited (BabeintheWoods) : 7/31/2012 7:18:08 AM (GMT-6)

I've had this going on now for over ten years. I've since become a successful competitive cyclist. If I had a dime for every time they had me rushing off to get surgery, I'd own my own island by now. Don't sweat it. How many people get cancer that never had dysplasia.