Posted 9/6/2012 4:27 PM (GMT 0)
My GI had me split mine. When I was on 40 mg, I took 10 mg at breakfast, lunch, dinner, and bedtime. When I dropped to 30 mg, I stopped taking the bedtime dose, etc. Once I got to 15 mg, I just took it all at once in the morning. He explained why, and if I remember correctly, it was because taking smaller doses throughout the day was less likely to suppress the adrenal glands than taking 40 mg all at once -- I think because the adrenals release the most cortisol in the morning.
I could just be making all that stuff up, though. ;)