This is constantly intersecting with thrombosis - clotting.
Mutations may lead to decreased or increased activity of enzymes. This may have different consequences, depending on the normal function of the serine protease. For example, mutations in protein C, when leading to insufficient protein levels or activity, predispose to thrombosis.
This sounds bad for my
Nattokinase :
Nattokinase is a systemic enzyme isolated from the traditional Japanese
soy food, natto. It has been shown to support healthy blood flow by assisting the circulatory clearing system of the body.
Blood clottingEffects of nattokinase, a pro-fibrinolytic enzyme, on red blood cell aggregation and whole blood viscosity.
Clin Hemorheol Microcirc. 2006. Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
A fibrinolytic enzyme, termed nattokinase, can be extracted from natto;
the enzyme is a subtilisin-like serine protease composed of 275 amino acid residues and has a molecular weight of 27.7 kDa. In vitro and in vivo studies have consistently demonstrated the potent pro-fibrinolytic effect of the enzyme. Blood samples were incubated with nattokinase for 30 minutes at 37 degrees C. Our in vitro results showed a significant, dose-dependent decrease of RBC aggregation and low-shear viscosity, with these beneficial effects evident at concentrations similar to those achieved in previous in vivo animal trials. Our preliminary data thus indicate positive in vitro hemorheological effects of nattokinase, and suggest its potential value as a therapeutic agent and the need for additional studies and clinical trials.
Wow
Plasmin is an important enzyme present in blood that degrades many blood plasma proteins, most notably, fibrin clots.
Camostat Mesilate inhibits plasmin - sounds like your playing with fire here.
Post Edited (aguywithuc) : 3/23/2013 7:38:23 PM (GMT-6)