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Ulcerative Colitis
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Posted 4/6/2013 3:07 AM (GMT 0)
How long does it take Imuran and other meds to get into your system? I usually take my meds (Imuran, multi Vit, calcium capsule & probiotic) around 6 pm. For the last 2nights, around 8 pm I have thrown up. I did not see any of the tablets or capsules in it, but I have wondered if it was in me long enough to do any good.
Posted 4/6/2013 4:54 AM (GMT 0)
I get my daily 10min nausea feeling about 1.5h after I take them. Are you taking them with food?
Posted 4/6/2013 12:18 PM (GMT 0)
Yep. I've been taking all ths for almost a year now and only recently started with problem. It really isn't nausea. It's just when I go to the bathroom, I gag and vomit. No nausea otherwise.

I have an appointment with my GI in 2 weeks.
Posted 4/6/2013 1:41 PM (GMT 0)
Try taking your Imuran right before you go to bed and not with other meds. If you get nausea you won't know it because you will be sleeping.
Posted 4/6/2013 3:43 PM (GMT 0)
It's not the meds making nauseous. It is the pushing to poop. I am absolutely fine until I go to the bathroom. Something triggers a gag response when I poop. Not so much pain, but just gagging and vomiting. I just wonder if I am getting any benefit from meds if I am taking them then throwing up 2 hours later.
Posted 4/6/2013 3:44 PM (GMT 0)
It is difficult to state with any precision how long ingesta remains in the stomach, small intestine and large intestine. Nonetheless, there have been many studies on GI transit, and the table below presents rough estimates for transit times in healthy humans following ingestion of a standard meal (i.e. solid, mixed foods).

50% of stomach contents emptied 2.5 to 3 hours
Total emptying of the stomach 4 to 5 hours
50% emptying of the small intestine 2.5 to 3 hours
Transit through the colon 30 to 40 hours

Remember that these are estimates of average transit times, and there is a great deal of variability among individuals and within the same person at different times and after different

Carlie

reference*http://www.vivo.colostate.edu/hbooks/pathphys/digestion/basics/transit.html*
Posted 4/6/2013 4:17 PM (GMT 0)
46- is there any pattern to your bathroom calls right now? how frequently are you going? are you going at night once asleep?

If you know it's the BM causing the vomiting, then try to find a window (maybe chart for a few days) where you typically do not use the washroom for a 4-6 hour window?
Posted 4/6/2013 9:59 PM (GMT 0)
Usually I go in the morning and then again before bed. My bms are small but solid.

Early in this UC journey, I was experiencing this but it came with numerous trips to the potty with diarrhea. If I ate, I pooped and threw up. I am not as bad as that since poop is formed and the frequency is no where near back then. Maybe it's a bug that will pass.
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