matrices said...
Psyllium seed powder is awful to consume all around - taste, texture - but the actual seeds aren't bad at all, mixed into yogurt.
Meanwhile: anyone else here besides aguy (1) tried RS and (2) seen results?
I stopped p-seed powder when I found RS for that reason.
www.ncbi.nlm.nih.gov/pubmed/10647628Dietary resistant starch and chronic inflammatory bowel diseases.
These studies were performed to test the benefit of resistant starch on ulcerative colitis via prebiotic and butyrate effects. Butyrate, propionate, and acetate are produced in the colon of mammals as a result of microbial fermentation of resistant starch and other dietary fibers. Butyrate plays an important role in the colonic mucosal growth and epithelial proliferation.
A reduction in the colonic butyrate level induces chronic mucosal atrophy. Short-chain fatty acid enemas increase mucosal generation, crypt length, and DNA content of the colonocytes. They also ameliorate symptoms of ulcerative colitis in human patients and rats injected with trinitrobenzene sulfonic acid (TNBS). Butyrate, and also to a lesser degree propionate, are substrates for the aerobic energy metabolism, and trophic factors of the colonocytes. Adverse butyrate effects occur in normal and neoplastic colonic cells. In normal cells, butyrate induces proliferation at the crypt base, while inhibiting proliferation at the crypt surface. In neoplastic cells, butyrate inhibits DNA synthesis and arrests cell growth in the G1 phase of the cell cycle. The improvement of the TNBS-induced colonic inflammation occurred earlier in the resistant starch (RS)-fed rats than in the RS-free group. This benefit coincided with activation of colonic epithelial cell proliferation and the subsequent restoration of apoptosis. The noncollagenous basement membrane protein laminin was regenerated initially in the RS-fed group, demonstrating what could be a considered lower damage to the intestinal barrier function. The calculation of intestinal short-chain fatty acid absorption confirmed this conclusion. The uptake of short-chain fatty acids in the colon is strongly inhibited in the RS-free group, but only slightly reduced in the animals fed with RS. Additionally, RS enhanced the growth of intestinal bacteria assumed to promote health. Further studies involving patients suffering from ulcerative colitis are necessary to determine the importance of RS in the therapy of a number of intestinal diseases and the maintenance of health.
en.wikipedia.org/wiki/Resistant_starchUlcerative colitis
Foods naturally rich in resistant starch may be beneficial in individuals with ulcerative colitis. One study presented at the 7th Congress of European Crohn’s and Colitis Organization (ECCO) meeting, Feb 16-18, 2012 in Barcelona, Spain found that resistant starch combined with wheat bran
effectively treated ulcerative colitis.www.ecco-ibd.eu/publications/congress-abstract-s/item/p208-abnorm.htmlAbnormal fibre utilisation and gut transit in ulcerative colitis in remission: A potential new target for dietary intervention
Conclusions: Fibre utilisation in the gut of patients with UC in remission is impaired. High WB/RS supplementation enhanced fibre utilisation and normalised WGTT. As it is well tolerated, its corrective effect on fermentation and transit may translate into therapeutic benefits during remission in patients with UC.
Some people and some mice benefitted :
These studies were performed to test the benefit of resistant starch on ulcerative colitis via prebiotic and butyrate effects. Butyrate, propionate, and acetate are produced in the colon of mammals as a result of microbial fermentation of resistant starch and other dietary fibers. Butyrate plays an important role in the colonic mucosal growth and epithelial proliferation. A reduction in the colonic butyrate level induces chronic mucosal atrophy. Short-chain fatty acid enemas increase mucosal generation, crypt length, and DNA content of the colonocytes. They also ameliorate symptoms of ulcerative colitis in human patients and rats injected with trinitrobenzene sulfonic acid (TNBS). Butyrate, and also to a lesser degree propionate, are substrates for the aerobic energy metabolism, and trophic factors of the colonocytes. Adverse butyrate effects occur in normal and neoplastic colonic cells. In normal cells, butyrate induces proliferation at the crypt base, while inhibiting proliferation at the crypt surface. In neoplastic cells, butyrate inhibits DNA synthesis and arrests cell growth in the G1 phase of the cell cycle. The improvement of the TNBS-induced colonic inflammation occurred earlier in the resistant starch (RS)-fed rats than in the RS-free group. This benefit coincided with activation of colonic epithelial cell proliferation and the subsequent restoration of apoptosis. The noncollagenous basement membrane protein laminin was regenerated initially in the RS-fed group, demonstrating what could be a considered lower damage to the intestinal barrier function. The calculation of intestinal short-chain fatty acid absorption confirmed this conclusion. The uptake of short-chain fatty acids in the colon is strongly inhibited in the RS-free group, but only slightly reduced in the animals fed with RS. Additionally, RS enhanced the growth of intestinal bacteria assumed to promote health. Further studies involving patients suffering from ulcerative colitis are necessary to determine the importance of RS in the therapy of a number of intestinal diseases and the maintenance of health.
www.ncbi.nlm.nih.gov/pubmed/10647628In Japan, these fiber-filled starches are already being used to treat ulcerative colitis, while in developing countries it’s used to remedy chronic bowel issues. New findings show that resistant starch can combat pre-cancerous cells and scientists in South China are using resistant starch to coat drugs for tailored cancer therapies, where they can target specific zones of the colon. “There is promising data leading to the treatment and prevention of colorectal cancer,”
More than you want to know..
physrev.physiology.org/content/81/3/1031.full.pdfPost Edited (aguywithuc) : 7/21/2013 9:59:11 AM (GMT-6)