I've heard and dealt with the negative side effects of Prednisone while on the drug, but has anyone had symptoms when they quit taking it? I tapered off and yesterday was my first day without it and I've been bat crap crazy since. I've had the huge mood swings, anger, unexplained rage, depression, and random bouts of crying in public. I wasn't like this before Pred, and I'm hoping it's only a temporary lingering of this God awful drug. I'm really stuggling to get through the day right now and unfortunately, I have no one to talk to who'd understand. Not sure if it's relevant but I also have started taking Cumcurin, Tumeric, and Slippery Elm, but I don't think natural medicines would make me feel this depressed and be this psycho. HELP!