Grape Seed Extract Results

Lmethyl is the bioavailable form of folic acid. I think it would be better for you then folic acid.

For your collection:

Novel Cell-Based Method To Detect Shiga Toxin 2 from Escherichia coli O157:H7 and Inhibitors of Toxin Activity
aem.asm.org/content/75/5/1410.full

The paper is actually on a method of detecting bacterial toxins, but interestingly the compound they chose to use to prove the technique was Grape Seed Extract. Works pretty darn good at blocking/interfering with bacterial toxins according to their results.

Falls in line with the WOO stuff as well.

As mentioned I responded exactly like you (but to WOO/Thyme) and at a high dose seemed to make things a little worse. I stayed at a lower dose for some time (a few months), then last week upped it again to a higher dose for the heck of it with excellent results so far - like once a day normal poop. This would be the equivalent to your three capsules perhaps.

It's funny when we try these things and have nothing really to go by other than "gut" instinct. Pun intended. And the fear of what if we change something and things get worse again. I hate this darn disease.

For those interested, I started GSE (exact same brand and dose as gary - had to get mine freight forwarded to Australia because they only deliver to US addresses). Anyway, first week started at 1 capsule. Thought i saw improve but it faded at the end of the week. Started 2 capsules last week end and havent seen any improvement. Been on GSE nearly two weeks now.

I am having my doubts but will give it a month.

my diet is low carb/ paleo feel awesome

Gary have you had any side affects from the extract

So it turns out WOO/Thyme and I think Grape Seed Extract effect mast cells. So they act similar to antihistamines in a way.

Just wanted to make you aware.

www.ncbi.nlm.nih.gov/pubmed/23088772 This isn't what I wanted to post but can't find the correct study at the moment. If you search Carvacrol effects on Mast cells etc you'll find some good info.

Anyway, I keep thinking about the "food allergy" side of things and your thought on IBD being more of an allergic reaction or disease.

In any case the oils seems to reduce inflammation and effect/dampen the humoral type allergic response.

My brain has cleared recently and I am back in full research mode. I really feel good, at least in my case, that my whole thing is related to a histamine mast cell thing brought on my broad spectrum antibiotics and high stress levels at the time of diagnosis. I am going down this one road right now with blinders on, trying to stay focused on this one area. I am currently searching for probiotics that help with this histamine mast cell thing. Apparently many probitoics can raise histamine levels, some are neutral, and some actually decrease histamine, mostly by increasing histamine degradation. I had a bad day the other day (one) after having a histamine overdose caused by eating high histamine foods and not taking enough DAO to counter it. I'm also very close to pulling the trigger on getting another stool analysis, this time with Ubiome instead of the American Gut I did before. The results will be very interesting.

That's what I take and it helps tremendously. Made a big difference but I don't think it will work in everyone. I believe my previous posts in this thread explain the reason I take it.

Still taking two per day. I had tried three per day at one point and it made me worse but have been considering trying that again.

@Kiptyn - That's awesome. Congrats on feeling a little better! Must be nice to have a bit of a break from the daily UC grind. To cool.

@Gary
Bactericidal effect of grape seed extract on methicillin-resistant Staphylococcus aureus (MRSA)/www.jstage.jst.go.jp/article/jts/35/3/35_3_357/_pdf

Forgetting the whole MRSA thing altogether - they imaged the effect of Grape Seed Oil on the bacteria. Interestingly (and perhaps not so surprisingly) Grape Seed Oil (on various bacteria aside from MSRA in other studies) has the identical effect WOO has on various bacteria - essentially making them "spill out their guts" for lack of a better term - see the above paper were they imaged them.

More interesting and important is some people ARE in fact responding to either to your Grape Seed Oil or the WOO thing. I've also noticed a few that did not respond (to WOO) seemed to give up fairly quickly (a few weeks), whereas the few that stuck it out (for a few months) seem to have a fairly remarkable changes. This seems to perhaps hold true to Grape Seed Oil as well.

So it seems there's two, natural, realistic, and easily accessible compounds - Grape Seed Oil and Wild Oregano Oil that people could try and perhaps see a lot of benefit from if they gave it a good honest go. Maybe not everyone, but heck, even a small percentage with substantial improvement is great if there's consistent results.

I'd like to hear from some others that might have tried or be currently trying this.

Also - One quick question. I noticed you take Vit D - I did not see my major "click" and return to normal once a day poop till I added 10,000I.U. of Vit A along with Vitamin D with each dose of oil. I'm curious if you or anyone else tried this as well and if it helped?

I know Tunnel on here seemed to see some results from the two combined. Would be interesting to find some valid options that help manage symptoms in both forms of IBD........ Even if they had to be combined with traditional meds for optimum results.

I forgot about the staph thing on your part. I think we're stuck experimenting and guessing and hopefully not ending up worse again. For me, I also get worse when I add to much WOO. So that is another parallel. I tried to stick it out but gave up and dropped to a lower dose. Was nervous to push things in the wrong direction. Though I feel great, the wrong food can trigger loose stool the next day. So diet (avoiding known trigger foods) must be an important aspect of the two.

Like you I was wondering if I should add Grape Seed Extract or maybe try alternating or well... I have no idea what to do, haha. I'm still terrified that whatever I'm doing will stop working one day.

Most frustrating part for me is being locked in this remission like state but at the same time knowing there's still something off - or not quite right, if that makes sense.

EDIT: My thought is maybe don't rock the boat and just keep doing what seems to be working for you. Same with me.