What to do?!? Constant loose/watery bowel movements

I am a 24 year old male who was diagnosed with ulcerative colitis (pancolitis) in 2009. I am aware that symptoms include bloody stools and diarrhea but I still have yet to have a normal stool and its really impacting my life.
Currently having 10-15+ often bloody and urgent BM's a day since my flare started and in August of 2013. Sometimes it seems that my body just wont absorb water or breakdown food properly. Also have had 3 different C-diff attacks over 3 years and I have never felt the same. Currently on 20 mg prednisone and 4800 mg asocal daily. Was in a humira drug trail which made me very sick and had to be hospitalized for 5 days. Now attempting to get into a new Pfizer drug trail because nothing else is working. I am at ends with this disease, it seems that I may never feel relief or remission again. I really cant't remember a time when I had felt "normal" and not having to worry or suffer from anxiety.

Any help or comments would be helpful. I am just not sure what to do next. I am getting lost in life. Not working, have become distant from friends, impacting my relationship with my girlfriend and often feeling angry or depressed at the entire situation. I feel as though the world is just passing by me while I sit at home close to a washroom waiting for that next urgent BM. Is surgery my next option ? I don't know. This had become more of a rant than an actual forum but I don't know how to help myself anymore. I would always tell myself, "just a few more weeks and I will be normal again". 5 years later, it seems it has only got worse than ever. I have tried different diets and medications and have yet to see any improvement. Except maybe when I am on 40mg of prednisone for about 2 weeks, I would have a few good days to actually go out and enjoy myself in the afternoon.

I know there are others out there like me, so what do we/you do next? So sick of waiting for trials and different medications to actually work.

I have been told that since 2009 when it was pancolitis that it is now left sided UC. I do take acidophilus and another probiotic daily. Currently not on any rectal meds, but I have used Pentasa and Salofolk suppositories. At the time they did not make much of an improvement. Is it possible that having been on vancomycin three different times has destroyed any good or bad bacteria that had been in my gut? Or that the cdiff has destroyed the lining of my colon to the point of no return?

What's the other probiotic you're taking?
I take what's in my signature.

It's a huge plus if your UC's healed to just left-sided. To where exactly?....up to the splenic flexure or just into the sigmoid?

Have you been checked at this point to see if you have c.diff?

You could try taking a fibre supplement...even such as Metamucil smooth (not the kind that's sugar-free)..

How are you eating?

What other supplements are you using?

q

Sorry to hear you are having so much trouble. I can definitely relate, especially the thought of the world passing by. But, as I am still learning myself, it will get better. And when you are feeling well, every day will be amazing because of it!

Have you tried going on a liquid/fresh juice diet for a week or two? I was having similar symptoms to you a couple weeks ago, and decided to try a strict juice fast for a few days. It seemed to help me and give my insides a chance to rest. Someone has also recommended, in addition to juice, to have aloe gel/aloe juice (the real kind, not the sugar stuff) and spirulina when you get up in the morning. I haven't tried those, but maybe it could help.

Good luck, hang in there.

Yes thanks parallelograms, I actually just bought a juicer so I will try a juice/liquid diet for a week or so to see if that helps. Also picked up some aloe-vera juice to add too.

Thanks Kazbern, I will ask my GI for some enemas or suppositories to help. I have been on them before and will try them again. I have used pentasa and salofolk, not sure if there is anything better. I have heard of procto-foam which I was also looking into.

Hey jacket fan. Yes I was on humira for about 3-4 weeks in which I saw zero improvement. Then I was on an increased dosage of weekly humia injections which made me very sick. Sounds similar to what you have experienced. Flu like symptoms including fever, nausea, bad diarrhea, headaches and just feeling very weak and constantly tired. the fever was about 102-103 for about 3 days until I went right to the hospital. I ended up in the hospital for 5 days after immediately stopping humira. For me it did not work at all, that is why I am skeptical about remicade because they are somewhat similar with that TNF blocker or whatever.

Interesting. For me, very achy, shivering uncontrollably, fever, weak. ER doc did not think Humira. He thought infection. That was the third time it had happened since I've started Humira. Good luck.