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Ulcerative Colitis
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Posted 12/6/2014 7:32 AM (GMT 0)
I researched this last time and got some. I never took it. I just looked and I still have it. I think I am going to give it a go. However, they exp last April. In researching further I think that the exp date is not valid and they have a much longer shelf life.

And yes I am willing to do scd diet Gary! 😊
Posted 12/6/2014 3:58 PM (GMT 0)
Ok texted my dr and asked for his support for LDN and he said ok. I start 1.5 mg today. Wish me luck ! Please!!!!!

What is the dosage regime. I start at 1.5 this month and slowly move to 3 - 4.5?
Posted 12/6/2014 8:53 PM (GMT 0)
I started at 1.5 mg, but I had to move down to 1 mg then moved slowly to 3 mg. Anything over that, my tummy just doesn't like it. I had some nausea when upping my dose. And also had some sleep issues, so I took it straight at 9 pm.

I went Paleo for the medication. Once I got in remission, I found I didn't need to be so restrictive. I can now eat some processed and wheat products with no issue.


Good luck!
Posted 12/6/2014 9:39 PM (GMT 0)
Thank you Sibby. If it gives people sleep issues, I read that elsewhere, why not take it in the morning??
Posted 12/6/2014 11:51 PM (GMT 0)
Some have said that when they took it in the morning, they started seeing symptoms again. These were all anecdotal, so I'm not sure if there is enough evidence to prove that. However, on LDNScience, it says you can take any time throughout the day.

This is from another forum: "It is generally recognized that the most effective time to take LDN is at bedtime, between 9 pm and 3 am, due to the fact that the endorphins for each day are always produced at their peak rate in the pre-dawn hours. A 9 am dosage time, as was used in this trial, might conceivably suppress—rather than boost—a patient's immune system.
Low Dose Naltrexone (LDN): The German MS Study "
Posted 12/7/2014 2:03 AM (GMT 0)
That is interesting! Thank you.
Posted 12/7/2014 10:45 PM (GMT 0)
@Sibby,

A few questions
- You started at 1mg, and ramped it up every month?
- What dose did you continue at the end?
- Whats your current status with regards to UC and LDN use to maintain remission?
Posted 12/7/2014 11:36 PM (GMT 0)
1. I went up .1mg every two weeks, or less, because every time I went up a lot .5 - 1 mg, I always felt pretty sick. This may be because I'm sensitive to some medications. You can go up from .5 to 1 mg every month, if you wish. Just watch how it bothers you.

2. I was at 3 mg, no more than that. I messed up a while back (forgot to take it for a little while), and had to go back down to 2 mg. I'll going back up to 3.

3. Complete remission. Can eat wheat without a problem. Anywhere from 2 to 3 mg. No symptoms/side effects from the meds or illness.
Posted 12/8/2014 5:12 AM (GMT 0)
That's great you are in remission. I think I need to research but I think I will step up 1.5 to 3 mg in one month and stay there and see what happens! My pills come in 1.5 dose. I hope this works!!!
Posted 12/8/2014 6:55 PM (GMT 0)
Good luck!

If you do not see a response, please think about getting fresher pills. I actually did notice a big drop in efficacy with old pills when I was on LDN (to the point where I no longer trusted the hospital compounding pharmacy (they made new batches every 6 months - I got a batch due to expire and I got worse...got a new batch the next month and got better) and had my gastro send a script to Skip's in FL).

I started right at 4.5mg and took my pills at bedtime (I found that if I took them earlier in the evening, I was less likely to be groggy in the morning). I noticed an effect within a week or two.

Unfortunately, for me, LDN just wasn't enough. It helped, definitely, but my colon still looked pretty bad when I was scoped. So, on to other things...
Posted 12/8/2014 9:55 PM (GMT 0)
I am curious if anybody made LDN at home, by dissolving 50mg tablet in 50ml water and storing it in fridge during the use.
Posted 12/8/2014 11:28 PM (GMT 0)
I called for a new script today! I think I might start taking at night cause I could nap during the day right now. I don't think I would have a sleeping prob. Will see when I get new pills. So far so good! Knock wood! I jinx myself all the time!
Posted 12/10/2014 3:31 PM (GMT 0)
I'm doing that, Delta. Works well for me, and is a hell of a lot cheaper than buying the pills every month.


Good luck, DMC!
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