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Ulcerative Colitis
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Posted 3/2/2015 10:44 PM (GMT 0)
I have been bleeding dr said fissure, but I think inflammation to. Lots of blood, urgency. I am using cortifoam, Canasa and ditilizam and on humira, when will the Canasa kick in. I have a lot of gas too, so take gasx to relieve pressure bcz it puts pressure on fissure. I also sometimes just poop blood.
Posted 3/2/2015 11:32 PM (GMT 0)
From my understanding canasa isn't for long term use, but people use it anyways to soothe any residual inflammation on the left side. The time period appears to be within 6 weeks, so I would expect to kick in around that time. When I used it, it was next to instantaneous.

From the site pdf:
CANASA works at the site of inflammation.
In clinical studies, CANASA was shown to be
effective in relieving symptoms of UP, such as rectal
bleeding and stool frequency, at 3 and 6 weeks.

It is not known if CANASA is safe and effective
for use for longer than 6 weeks. It is not known if
CANASA is safe and effective in children.
Posted 3/2/2015 11:38 PM (GMT 0)
Thats scary i have been on it since nov!!!!
Posted 3/3/2015 12:07 AM (GMT 0)
plenty of people have been on it long term. they only did the clinical study for 6 weeks, so they have to say that - but there is plenty of post-market info now and it seems to be safe
Posted 3/3/2015 12:44 AM (GMT 0)
I have been on Canasa for 4 days..been on cortifoam a month.
Posted 3/3/2015 1:03 AM (GMT 0)
You can be on canasa long term, there is no harm in it. It's an anti-inflammatory medication.
Posted 3/3/2015 1:12 AM (GMT 0)
How long does it take to see improvement is my concern?
Posted 3/3/2015 1:21 AM (GMT 0)
Most meslamine works pretty qickly, 2-3 weeks to see a response. It depends how badly inflamed your uc is, and whether or not, you respond to it.

Good luck,
i💩
Posted 3/3/2015 1:27 AM (GMT 0)
Ok, it's been 4 days since being on the canasa.
Posted 3/3/2015 1:53 AM (GMT 0)
You can be on canasa long term, there is no harm in it. It's an anti-inflammatory medication.

I'd rather not be a test dummy. I'm hoping people learned from the vioxx death toll that drugs need far more stringent requirements and testing methods.

I think it's very important for drug manufacturers to invest in long term clinical trials and canasa is not an exception.

From my previous experiences, I, personally, would not opt to be on it long term, but everyone has to make a choice.
Posted 3/3/2015 2:24 AM (GMT 0)
Unless you have an intolerance to it you can be on Canasa forever. There have been many test dummies that had zero problems and I don't know of anyone who has actually ever had a problem unless they were intolerant to it. In fact, it can decrease colon cancer risks.
Posted 3/3/2015 3:52 AM (GMT 0)
If they don't have any data beyond 6 weeks, they can't say anything about colon cancer prevention. I think it's a joke to be honest.

Again, I question why they were not able to extend the trial to provide more consistent, long term data. It reeks of shadiness to me.

It is also possible to build up intolerance to medication after taking it for a while, and this is why a drug like canasa needs longer clinical trials.
Posted 3/3/2015 4:00 AM (GMT 0)
There have been many here who have taken Canasa as well as oral mesalamines for decades with no issues. We don't need a study. We've already done it ourselves, usually with doctor's approval.
Posted 3/3/2015 4:12 AM (GMT 0)
I don't need testimonials. I need studies showing long term safety if I am going to put it in my body.
Posted 3/3/2015 4:21 AM (GMT 0)
But the studies are done by Big Pharma so you wouldn't believe them anyway. I'm sure Monsanto and the FDA would be in on it too.
Posted 3/3/2015 5:31 AM (GMT 0)
I think it's just a form of 5asa which is safe, I think
Posted 3/3/2015 6:01 AM (GMT 0)
msm - as people will tell you here - everyone responds differently. I've just finished being on Canasa for 4 weeks and I (knock on wood) haven't seen blood in about 5 days and the last week or two it's only been a drop here or there after bleeding a lot more loosely after each bm. I did notice an improvement quickly but it took some weeks (as well as 4 lialda every day) to get this to start to clear up.

Best wishes
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