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MP6 make anyone else pee?

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Ulcerative Colitis
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Posted 4/8/2015 2:56 PM (GMT 0)
Hi all,

Been on MP6 for a month now, which seems to be helping my flare; it's really tapering off and I can actually leave the house without a diaper sometimes (phew). So far I've been okay, no discernible side effects apart from some nausea the first week. The problem now is that I can't get through 2 hours during the night without having to get up to pee. It's not getting up to bolt to the loo lest I have an unwanted bowel movement, so I guess that's an improvement, but having to get up every 2 hours is not conducive to a restful night's sleep.

Just wondering if anybody else has experienced this...

 

Posted 4/8/2015 3:01 PM (GMT 0)
it does play with water elimination. I think there is a warning on the bottle to drink lots of fluids. I did not see it, and I got a kidney stone.
Posted 4/8/2015 3:14 PM (GMT 0)
I'm taking 6MP but it hasn't kicked in all the way yet. My doctor says it takes around a month. I've been taking it since March 16.

Anyway, no peeing issues for me.
Posted 4/8/2015 4:32 PM (GMT 0)
Hmm never heard of 6mp causing increased urination. I looked up side effects and that wasn't listed.www.mayoclinic.org/drugs-supplements/mercaptopurine-oral-route/side-effects/drg-20064683
Posted 4/8/2015 4:37 PM (GMT 0)
Sometimes when the diarrhoea slows down and the bowel gets a chance to absorb water again, extra peeing can occur. It can take time to settle but hopefully it is a good sign.
Good luck.
Posted 4/8/2015 5:11 PM (GMT 0)
THANKS PEOPLE! I have a follow up next Wednesday with my GI so I will ask him about the peeing too and let you know.

Michele JC - you've been taking 6MP only about a week less than me. I do think they've begun to work but only in the last week or so so if you are anything like me you can look forward to imminent relief!
Posted 4/8/2015 6:06 PM (GMT 0)
I e been on 6 weeks and no bllod but last couple of days still have urgency with solid poo, i think i am getting there, slow but sure. Always have to pee!
Posted 4/8/2015 6:10 PM (GMT 0)
Winniethepoop: I am taking the Uceris along with the 6MP. I am noticing a good improvement but its slow. I plan on dropping the Uceris once the 6MP kicks in all the way.
Posted 4/9/2015 12:49 PM (GMT 0)
Some people say you don't have to taper from uceris but my dr and pharm said you should. I am using budesonide to taper. Also just to stay on a lower dose until I see really good improvement for a long time.

So now I am on 6mg for a couple more weeks then 3 meg for a couple weeks.

Just something to think about! Good luck!
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