Cant get the whole paper but enough info is there. Small trial but useful info.
1996. 4 out of 9 into remission.
Click on look inside if the paper does not come up automatically.
Looks like you need 66 ugm/day to fully express Gpx.
Also note greater than 100 u gm/day for prolonged periods can be toxic.
Old Mike
http://link.springer.com/article/10.1007/BF02034441#page-1
Seems that there is something else going on.
In Swidsinski's pictures there is always lots of leukocytes/neutrophils trying to defend the colon from
invading bacteria. In the above extra selenium protects the tissue from ROS. If selenium deficient there is not enough GPx to protect the neutrophils from their own oxidative bursts, so they die quick after killing only a few bacteria
http://jn.nutrition.org/content/133/5/1457S.full
more
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2274988/
the can also help to heal
http://www.pnas.org/content/110/31/12768.abstract
Just suppose in the initial UC attack if we are selenium deficient,and the neutrophils are weak.
This might be part of the impaired barrier defense. Long shot I know.
this might be interesting selenium in American soils, will try and track down the rest of the world
notice Canada with high rates of IBD it is low.
http://support.dietpower.com/diet/selenium.htm
Post Edited (Old Mike) : 4/12/2015 7:51:29 AM (GMT-6)