have I been misdiagnosed?

I'll try and keep this short. For almost three years now, I've been suffering from bouts of gas, bloating, small stools, and sometimes very frequent small stools like im dealing with right now. I've only suffered from diarrhea when my symptoms first started all that time ago and when I got food poisoning last Halloween which prompted my colonoscopy. I've always been a little leary of my diagnosis as my symptoms just never seemed to really line up with UC. I've never had blood, I've only experienced bad diarrhea for relatively short periods of time, and I've never really had any bad pains. I decided to get a second opinion, and the GI I saw yesterday is questioning my diagnosis as well, he's thinking it sounds more like IBS. I asked him why my current GI saw inflammation during the colonoscopy, and he thinks its possible that it was inflammation leftover from the food poisoning. Furthermore, he looked over my report and was surprised that there was no documentation of any crypt abscesses, apparently they're common with UC. Needless to say, I'm a bit dumbfounded and really getting ready to lose it. He told me taper off of Uceris as he thinks this will give us a good idea if I'm really flaring or not, and quite frankly, I'm ready to stop the purinethol as well and start from scratch.

Can anyone weigh in on this?

Post Edited (mlf231) : 4/21/2015 9:39:05 PM (GMT-6)

as long as the crypt cells were deformed it says uc - don't know about abscesses

symptoms do sound like IBS

Nothing about crypt abscesses in my report at all

Crypt abscesses, crypt branching, crytptitis, etc are all common chronic histological findings for UC. If these were absent its possible you were misdiagnosed, but I wouldnt get my hopes up until you repeat the colonoscopy and biopsies

Given your uncertainty about your diagnosis, I would opt for a colonoscopy or a flexible-sigmoidoscopy. The flex-sig would be easier to prep for (only two fleet enemas) and does not require sedation, so it's way cheaper and easier. They take biopsies in both procedures.

You definitely need to re-scope, but a sigmoidoscopy with biospy might be enough. Fecal calprotectin would be useless since it wouldnt confirm IBD diagnosis. Its only useful for monitoring

Interested why you say that calprotectin useless Marauder? MLF said they'd like to know if they're in UC flare or not? A raised calprotectin is a marker for inflammation in the gut, not necessarily UC but inflammation at least. This would help MLF to know surely if there is inflammation now? MLF wondered if they had IBS now, a raised calprotectin would be unlikely if only IBS.

MLF - when I have had scopes when in remission they always write "quiescent colitis" and tell me they can see that colitis was active previously (independent of biopsy) but I am not sure what it is that tells them this.