Too much prednisone?

It is the standard beginning dosage. If your colon is not in good shape you can't expect miracles in just three days. How quick it works depends on a number of different factors.

i've never noticed any positive results from starting oral steroids. i always do iv steroids then transition to oral steroids. my dose is usually 40-45 mg although i know some people that have taken between 60-100 mg.

Overnight difference for me and that is why it is hard not to give in and take the medication. Last time I resiste but was not getting better so hopped on it. Felt like a new man, 2 months later I felt like an old man as all my connective tissue was falling apart. 60mg is not unusual in my history.

Given the problems it caused and the difficulty regaining energy after taper my aim is to never let things get that far out of control again.

IV suggests your liver is not able to convert prednisone to prednisolone. That happened to me once until I stopped another medication. Of course solumedrol saved me but stopping the other med allowed me to continue on oral pred.

Hi, no I would say that is an average starting dose. It all depends how ill you are when you start oral steroids. They can only give you a certain amount orally, and if your body needs a bigger dose then you would need to go into hospital for IV steroids.

For me personally I normally see results within a couple of days, unless of course I needed a larger dose, both times that has happened to me I have been hospitalised and put on IV steroids, which work very fast.

I'm currently in a flare myself, taking 40mg prednisolone daily (I live in the UK so we don't have prednisone). Fingers crossed it is working because it is day 3 for me too and I have been able to start eating again.

Some tips you might have heard already are to take them with food (ironic I know!) and to take them in the morning about 8-9am. I also take the calcichew tablets.

I did suffer side-effects the second time that I was in hospital. It didn't happen until after I had been home and on oral steroids a while I think, but I got 'moon face', which was really horrible as my hair had fallen out (due to the severity of the UC itself). It did eventually go away but it took a few months from what I can recall. Sorry I have a very bad memory.

I don't know if it counts as a side effect, but with both of my major flares (the ones where I was in hospital), I got physically dependant on the steroids, eg. when I was trying to reduce the dose, I would flare-up again at about 15 mg and have to go back up to the higher dose.

As for weight gain, I did notice it after my 2nd hospital stay also, but I really don't know what caused it, as I wasn't eating any more than normal. It could have been the steroids, or the fact I had just turned 30, or the fact that I was too ill to work or do any exercise for quite a while whilst I recovered. It certainly didn't go away once I had finished the steroids, in fact it has been slowly creeping up over the years, much more noticeably since I have been much less active than I used to be. Also I personally have to stick to a low residue diet, which makes losing weight through diet virtually impossible.

I have also suffered depression for about 4-5 years (managed to come off the anti-depressants a few months ago). The depression started in 2009 when my ex boyfriend left me, but got much worse when I was hospitalised in 2010, which I attribute to the UC itself rather than the steroids, as I have always had huge problems coping with the UC mentally.

I did have a 3 month flare from Dec 2014 - Feb 2015, and had no problems with the steroids, probably because it was over a much smaller time period.