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High liver enzymes

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Posted 7/29/2015 4:09 AM (GMT 0)
Hi ,
I've recently had a blood test and noticed that 2 of my liver enzymes are high . My AST is 77 and My ALT is 41. My GI is repeating blood test to check for liver disease . Has anyone had this experience ? Any input would be appreciated . I'm worried maybe medication is causing this ?

49 year old female
UC pan colitis for 21 years
Current meds: Asacol 12 pills a day
Salofalk suppositories 1 times a day
Finally in remission
Posted 7/29/2015 5:57 AM (GMT 0)
I had high liver enzymes once and my regular family doc told me to take milk thistle. Worked like a charm and my next test was in the normal zone. Worth a try.
Posted 7/29/2015 6:32 AM (GMT 0)
Thanks Gary , I'll give it a try .
Posted 7/29/2015 2:28 PM (GMT 0)
I have had high liver enzymes a few times.  But much higher than yours, like into the 100s.  The first time my GI at the time said it was probably just my flare/all the meds and they did no other tests, they did go back down.   The 2nd time I was with a new GI and they did further tests and I have PSC which is a complication of UC.

Now I wish the first GI would have done more tests because as high as they were I think I may have had PSC for a couple years before my new GI caught it.

Posted 7/29/2015 4:10 PM (GMT 0)
Those levels arent really that high; not enough to be overly concerned about. And neither of them are completely specific to the liver. The fact that your AST > ALT indicates that the source MAY be muscular, not hepatic. Worth bringing it up with him.
Posted 7/29/2015 7:37 PM (GMT 0)
When my levels were high they were well over 100. I think one of them was over 400. As soon as I stopped taking azathioprine they went back to normal for me -- which sometimes is a point below "normal". Not sure what low levels mean but my docs have never been concerned so I guess it's ok
Posted 7/29/2015 8:14 PM (GMT 0)
Marauder , Interesting that it could be muscular because I do run quite a bit . I will bring it up to my GI. I just don't want to end up with liver disease . Im wondering if Asacol could cause liver damage or is it the UC itself . Cupcakesingal, how would I know if I was developing PSC what are the signs and is there a way to prevent it from happening ? I've had many bouts of idiopathic pancreatitis over the last 20 years and I'm worried about PSC .

49 year old female with Pancolitis for 21 years
Current meds:Ascacol 12 pills a day
Salofalk suppositories 1 time a day
Finally in remission
Posted 7/30/2015 1:27 PM (GMT 0)
A lot of people with PSC don't have any symptoms, I think it is most often caught from irregular bloodwork and then further tests.   The only symptoms that the heptologist asked me if I had were itching or upper right quadrant pain where your liver is.   I never had any symptoms, it was my bloodwork that caused my Dr to send me for an MRI and they made the diagnosis from that.

From what I know there is really no way to prevent it most people who have it have had UC awhile.  I think I read 75% of PSC patients have UC or Crohn's but it is most common in UC.

There really isn't a treatment so for now I have just been watching my diet, no alcohol/no gluten, low sugar and trying to keep my toxic load to a minimum so my liver doesn't get over worked.

 

Posted 7/30/2015 1:51 PM (GMT 0)
A good drinking binge will do that.
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