Family members with ibd

My son had UC, he now has a pouch for the last 15 years, is UC hit at 21 mine at 32.
He failed all meds at the time, did not try biologics.
His UC perhaps induced by tetracycline/isotretinoin cream
I quit smoking 3 years prior to my UC.
Nether one of us can handle probiotics well, whether pills,yogurt or lacto fermented veggies in my case.
Too many bacteria from probiotics seem to cause a major problem in both of us.
Can't say much about food.
Old Mike

I have UC and IBS my daughter also has IBS
I live in NC ad she lives in Seattle WA
We both have the same food problems
Can't eat a lot of veggies or fruits ad meat is a big no no
I am 82 years old and she is 60!

Myself, my sister, uncle and cousin all UC. Uncle, sister and myself had severe pancolitis that required surgery because we didn't respond to meds. My cousin controls her UC with 6mp.

Edit: I forgot to add my mother has rheumatoid arthritis. Under control with Remicade treatments.

I am not aware of anyone in my family who had IBD. I unfortunately had a very drug resistant case.

these polls can't tell much.

the correlation of occurence of IBD and genes is very well established. The exact correlation varies depending on which of the 168 gene loci you look at. It is modest, typically r=.2 or lower because other factors besides genes are important too.

The question of the correlation of genes and prognosis is an interesting one. I have not seen work looking at it quite the way you ask. Too many other variables involved. But it has been studied how genes predict response to medications. For example: www.ncbi.nlm.nih.gov/pubmed/15058520

My mother had CD (died due to complications of CD when I was 10), my great grandmother had either UC or CD (there was no name for it back then) and my daughter has IBS.

My great grandmother lived in Wisconsin. And obviously I lived with my mother here in MI.

My mom had UC but didn't get it until a couple years after I got sick with CD...odd eh, usually it's the other way around. Obviously mine was triggered before hers, I was in my early 20's her in her mid 60's and I was no longer living at home (thank god) and already a wife and a new mom when I got sick.

Dr. Kevin Rioux did a small paper explaining IBD; the Genetics and inheritance that came in my CCFC journal years and years ago, they simply don't understand how it gets passed down genetically the way they can figure out other diseases that are also genetic/inherited but they do know there is some kind of genetic basis...they still have much to learn.

No IBD anywhere in my family. I'm just lucky, I guess.

My mother has irritable bowel with constipation and takes no medications for it. My aunt (on my dad's side) also has irritable bowel and takes anti-spasmatics for it. I'm the first with uc, no crohn's either, and my only sibling is fine (knock on wood). Everybody lived in a small area of nearby towns here. I think I have a definite genetic predisposition for bowel issues (down the maternal and paternal line). 20-ish percent of uc patients have at least one relative with ibd or ibs. I had no trigger that I can figure (no medications or antibiotics for 10+ years prior to my diagnosis).

I go it alone. No one in my family has anything like this. Supposedly one of my great grandparents had some kind of colon issue, but they don't know specifics. So far it looks like I standout in my family on both sides regarding UC. :shrug