Nitric Oxide/Inflammation-You had better believe it

There are conflicting studies on NO and UC.

If I take arginine which promotes NO I seem to get worse.

If I take lysine which inhibits NO I seem to improve,somewhat.

Old Mike

These will get you started if you want to research the subject.

Free full paper

http://www.ncbi.nlm.nih.gov/pubmed/18475670

http://www.ncbi.nlm.nih.gov/pubmed/7557576

http://www.ncbi.nlm.nih.gov/pubmed/12239458

 

CM: I know you get it in food,but it is balanced with lysine.
For me if I take arginine supplements I get worse,with lysine supplements I improve.

You may be in a state where NO is anti inflammatory where for me it is inflammatory.

NO is a double edged sword.

Old Mike

Post Edited (Old Mike) : 7/1/2012 9:44:37 AM (GMT-6)

DanthaMan said...
I took arginine-ethyl-ester after recommendation from a poster. I couldn't make it past two days on it because it made me much much worse.

I take it every day, probably the guy that recommended it. Every other variation of ethyl ester is disastrous for me. I have taken 10 pills one day there does not appear to be any sort of limit for me.

The studies are conflicting because UC people seem to have a lot of circulating arginine but its somehow unusable.

OldMike...How much L-Lysine do you take?

q

Old Mike,

Just wanted to chime in with a similar experience - supplemental lysine has helped with my UC (significant reduction in blood passed, likely due to healing promotion).

In a way it is depressing - I have had UC for 16 years and 75% of the items which have helped the most (psyllium, melatonin w/B6, and now lysine) I discovered on my own - and 2 of the 3 essentially by accident/trial and error.

(Meanwhile, a certain set of b*st*rds at a certain pharma co are working overtime to confirm and enhance the worst beliefs about pharma cos by having delayed (to date) generic Asacol for nearly three years...thanks for the original med research and patent system integrity d-bags...)

Back to lysine...a very brief scan of Pubmed didn't turn up much re lysine and colitis (I think, I was going pretty fast, I'll follow up...).

Ironically (and, again, depressingly) I *have* tried L-glutamine for a couple of times/months over the last 10 years (due to some positive Pubmed reports) but it really did almost nothing for me.

Meanwhile, lysine (also indicated to be a significant healing factor promoter - like glutamine - started to work for me in less than a week).

As I've mentioned before, I wish this site would cobble together some sort of cumulative "scoreboard" that would allow posters to list all the OTC products that have helped them (perhaps including a ranking of degree of help) and then allowing everyone else to "vote" their own personnel experience/ranking by listed OTC product.

The way things are now, a huge amount of individual product experience is being essentially lost - buried in thousands of individual posting streams where only chance and directed searches will ever find them.

There is no other way to say it...this seems pretty stupid and wasteful to me.

Why can't Healingwell create a simple OTC scoreboard as described?

I stopped lysine for what ever reason back in 2012.
Now just take curcumin, occasional biotin.

Stopped everything else.
Old Mike

I suspect the pressure would go back up given sufficient time after stopping
supplements,or you might have other reasons for low BP.
OM

Old Mike said...
I suspect the pressure would go back up given sufficient time after stopping
supplements,or you might have other reasons for low BP.
OM

Thank you for replying.